Kasper Dolberg scored twice as Ajax beat rivals Feyenoord 4-1 in the Eredivisie on Sunday.
Feyenoord won 4-0 at AZ to climb up to second, Ajax beat Heerenveen by the same scoreline while Vitesse and Utrecht drew 1-1.
Jurgen Locadia scored four goals as PSV Eindhoven trounced FC Utrecht 7-1 to climb to the top of the Eredivisie table.
Sparta Rotterdam 'keeper Roy Kortsmit went from hero to villain and back again as he saved the same penalty twice against AZ Alkmaar.
Wout Weghorst recovered from a double penalty miss to shoot AZ Alkmaar joint top of the Eredivisie with a 2-0 win at Sparta Rotterdam.
Heerenveen secured a surprise 2-0 home win over 10-man PSV Eindhoven on Sunday.
PEC Zwolle moved to the top of the Eredivisie with a 2-0 win at home to FC Twente on Saturday.
Eredivisie newcomers Venlo maintained their perfect start to the campaign with a 2-1 win at FC Twente.
Ajax suffered an opening-day defeat in the Eredivisie after losing 2-1 at Heracles.
Utrecht have qualified for the Europa League after overturning a 3-0 deficit against AZ to triumph on penalties in a dramatic play-off.
AZ Alkmaar took a huge step towards next season's Europa League after beating Utrecht 3-0 at the AFAS Stadion.
AZ Alkmaar will play FC Utrecht in the Eredivisie's Europa League play-off final after they negotiated semi-final ties.
Go Ahead Eagles can only strive for a play-off place in their unlikely bid to avoid relegation after they were beaten 3-2 by Groningen.
Steven Berghuis' double salvaged a point for Feyenoord as the Eredivisie leaders were held to a 2-2 at PEC Zwolle on Sunday.
Jens Toornstra scored a hat-trick as Eredivisie leaders Feyenoord thrashed struggling Go Ahead Eagles 8-0.
PSV Eindhoven moved up to second place in the Eredivisie after a 2-0 win at Sparta Rotterdam.
Feyenoord maintained their four-point lead at the top of the Eredivisie table with a comfortable 5-2 win over AZ Alkmaar.
Mathias Pogba struck the game's only goal as Sparta Rotterdam became the first team this year to beat Feyenoord in the Eredivisie.
Feyenoord scored late to beat PSV Eindhoven 2-1 and maintain their five-point lead at the top of the Eredivisie.
Lyon cruised through to the last 16 of the Europa League with a thumping 11-2 aggregate win over AZ Alkmaar.
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