PSV Eindhoven ended the weekend top of the Eredivisie after beating Utrecht 2-0 on Sunday.
Ajax blew the chance to go back to the top of the Eredivisie after conceding a stoppage-time equaliser against Roda.
PSV Eindhoven cut the gap on Eredivisie leaders Ajax to a single point with a 3-1 win at Excelsior.
PSV closed the gap to Ajax at the top with a 4-2 win over Twente, while AZ Alkmaar beat Feyenoord on Sunday in Eredivisie.
Ajax will take a three-point lead into the winter break after Riechedly Bazoer secured a 2-1 victory against De Graafschap.
PSV missed the chance to close the gap on Ajax at the top of the Eredivisie as they drew 1-1 at home to Roda JC.
Dirk Kuyt's impressive scoring form continued for Feyenoord on Sunday as the Rotterdam club beat Heracles Almelo 3-0 at home.
Davy Klaassen scored twice as Ajax Amsterdam trounced SC Cambuur 5-1 to extend their lead at the top of the Eredivisie.
Ajax maintained their three-point advantage over Feyenoord with a 1-1 away draw on Sunday, as PSV Eindhoven jumped into second spot.
Feyenoord lost ground in the Eredivisie title race after a shock 1-0 loss against ADO Den Haag.
Nigel Hasselbaink hit a 92nd-minute equaliser to earn Excelsior a 1-1 draw against PSV Eindhoven on Saturday night.
There were Eredivisie wins for both Ajax and PSV on Saturday, while second-placed Heracles slipped to defeat.
Heracles Almelo moved to the top of the Dutch league with a 2-1 win over champions PSV Eindhoven at the Polman Stadion on Saturday.
Ajax's Anwar El Ghazi scored twice in a 4-0 win over ADO Den Haag that took them clear at the top of the Dutch league on Sunday.
Luuk de Jond rescued a point for champions PSV, while their were wins for Heracles and Roda JC.
Michael de Leeuw rescued a point for Groningen in a 1-1 draw with Twente in the Eredivisie on Wednesday, as NEC beat Excelsior 1-0.
AZ claim a Europa League place at the expense of Feyenoord, who were consigned to the play-offs for a place in Europe.
NAC Breda face a relegation play-off, while Manchester United-bound Memphis Depay scored for PSV.
AZ Alkmaar remain in contention to clinch a Europa League berth from the Eredivisie after a 2-0 win at FC Twente.
Feyenoord moved a step closer to qualifying for the Europa League after a 2-2 draw at Willem II Tilburg in the Eredivisie.