Michy Batshuayi scored twice on Checkatrade Trophy duty as Chelsea's development squad reached the last 16.
Leicester City made it through to the last 16 of the Checkatrade Trophy while Swansea and West Ham's U21 sides were beaten.
Michy Batshuayi scored for Chelsea's U21s in the Checkatrade Trophy less than 24 hours after facing Atletico Madrid in the Champions League.
Chelsea's U23 side came from a goal down to beat Exeter 3-1 and progress to the second round of the Checkatrade Trophy on Tuesday.
Oxford United will travel to Gillingham in the second round of the Checkatrade Trophy.
Gillingham reached the last 32 of the Checkatrade Trophy with an astonishing 7-5 victory over Reading U21s.
Charlton twice came from behind to snatch a 3-2 win over Fulham U23s to reach the second round of the Checkatrade trophy.
Luton goalkeeper James Shea managed to get his red card changed to a yellow after pulling up the referee over new rules.
Only two Under-21 sides won as their lower-league opposition enjoyed the better of the Checkatrade Trophy second round on Tuesday night.
Wycombe boss Gareth Ainsworth is set to come out of retirement to get the club through its current injury crisis.
There was a busy night of Checkatrade Trophy action on Tuesday, with Man City, Everton, Spurs and West Ham all in action.
Sky Sports has strengthened its position as the home of football with a new deal to show live coverage of the EFL until 2024.
Man City and Tottenham have accepted an invitation to have their academy sides in the Checkatrade Trophy.
EFL chief executive Shaun Harvey thinks there is a positive future for the Checkatrade Trophy after a "rocky start" in its new format.
Struggling Coventry secured an unlikely Checkatrade Trophy triumph at Wembley with a 2-1 victory over Oxford.
Luton and Oxford United meet in the semi-finals of the Checkatrade Trophy on Wednesday, live on Sky Sports.
Ready for Oxford and geared for Sky Bet League One, Luton boss Nathan Jones talks to Sky Sports.
Coventry beat Wycombe 2-1 to reach the Checkatrade Trophy final and seal a spot at Wembley for the first time in 30 years.
Coventry City will play Wycombe for a place in the final of the Checkatrade Trophy at Wembley in April.
Draw for the third round of the Checkatrade Trophy.
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