Jorge Sampaoli led Sevilla to a 5-0 thrashing of already-relegated Osasuna in what could be his final game at the helm.
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Sporting Gijon were relegated despite winning 1-0 at Eibar, meaning Leganes and Deportivo avoided the drop.
Celta Vigo made changes with a Europa League semi-final against Man Utd in mind and fell to a 3-0 defeat against Athletic Bilbao.
Real Madrid remain level on points with Barcelona at the top of La Liga after a thrilling 6-2 win away at Deportivo.
Relive the action from Real Madrid's trip to Deportivo as they looked to bounce back from their dramatic El Clasico defeat.
Willian Jose headed the winner as Real Sociedad boosted their Europa League hopes with a 1-0 success over Deportivo La Coruna.
Atletico Madrid kept themselves ahead in the battle with Sevilla for third place in La Liga after a 3-0 win over Osasuna.
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Sevilla were celebrating victory for the first time in over a month after beating Deportivo La Coruna 4-2 in La Liga.
Osasuna boosted their improbable survival hopes by winning for only the second time this term with a 1-0 win at Alaves.
Sevilla are 10 points off the pace after being held to a 0-0 draw by Sporting Gijon, while Valencia beat Deportivo 3-0.
Antoine Griezmann starred as Atletico Madrid beat Sevilla 3-1 in La Liga, while Sporting Gijon and Celta Vigo also claimed wins on Sunday.
Barcelona's title hopes suffered a setback as they were beaten 2-1 at Deportivo La Coruna in La Liga on Sunday.
Recap the action as Barcelona's title hopes suffer a setback with a 2-1 defeat to Deportivo La Coruna.
Barcelona, Real Madrid and Sevilla will be looking to avoid any slip-ups in the La Liga title race this weekend.
Deportivo put five points between themselves and the La Liga drop zone after rescuing a late 1-1 draw at home to Real Betis.
Deportivo La Coruna triumphed 1-0 at Sporting Gijon on Sunday, as Las Palmas and Athletic Bilbao also claimed La Liga wins.
Atletico Madrid striker Fernando Torres left hospital on Friday morning after suffering a head injury in the 1-1 draw at Deportivo.
Sevilla moved to within two points of La Liga leaders Barcelona as Vicente Iborra's first-half winner earned a 1-0 win over Athletic Bilbao.