Barcelona visit Atletico Madrid before Real Madrid head to Villarreal in a crucial weekend in the La Liga title race.
Zinedine Zidane has hinted that he could rotate his squad as Real Madrid host Espanyol in La Liga on Saturday with Gareth Bale set to return.
The top four may all be short odds to triumph in La Liga but there are sub-plots aplenty as the action hots up this weekend.
Asier Illarramendi scored a stunning winner as Real Sociedad won 2-1 at Espanyol in La Liga on Friday evening.
Watch Asier Illarramendi's thunderbolt which secured Real Sociedad a 2-1 victory away at Espanyol.
Fernando Torres scored twice as Atletico Madrid won 2-0 at home to Leganes, as Eibar thrashed Valencia 4-0 and Espanyol won at Malaga.
Sevilla never fully recovered from the shock of losing their captain just two minutes into their clash with mid-table Espanyol.
The top three will be looking to avoid slip-ups in the latest round of La Liga fixtures, all live on Sky Sports.
Revista De La Liga will return to Sky Sports screens this week, hosted by Spanish football expert Guillem Balague.
Real Madrid will be looking to strengthen their grasp on top spot in La Liga once again as they go last on Sunday night.
We take a look at the top five goals from the La Liga action this weekend, including a stunning strike from Antoine Griezmann.
Valencia moved further clear of the La Liga relegation zone with a second straight win, beating Villarreal 2-0 at El Madrigal.
Valencia won in La Liga for the first time since October, beating Espanyol 2-1 at the Mestalla.
Espanyol's Javi Fuego missed from two yards out in the 91st minute during the La Liga draw with Deportivo on Friday.
Can Real Madrid get back on track? How will Barcelona and Atletico Madrid fare? A preview of the weekend's La Liga action.
Deportivo La Coruna were denied a first away win of the season as Espanyol hit back to earn a 1-1 draw in La Liga.
La Liga side Espanyol were dumped out of the Copa del Rey at the last-32 stage as second-tier Alcorcon forced a penalty shootout win.
Luis Suarez and Lionel Messi were the stars of the show as Barcelona beat Espanyol 4-1 in the Catalan derby on Sunday evening.
Relive the action as Barcelona saw off Espanyol 4-1 in the Catalan derby on Sunday evening.
Deportivo La Coruna beat Osasuna 2-0 on Sunday to pull four points clear of the drop zone, while Eibar drew 1-1 at Leganes.