Last Updated: 01/09/13 7:42pm
Sterling looks to seal the deal and his shot from just outside the United area is tipped over by De Gea.
Sterling breaks on the counter for Liverpool but has only Sturridge in support. He does enough though to win his side a free-kick on the left in the United half.
Van Persie takes the restart - the delivery is better but Enrique heads clear. There will be five added minutes.
Lovely pass from Hernandez through to van Persie for his first real chance of the game but his sliding attempt goes wide of the near post.
Long crossfield ball to Nanin on the right but his control lets him down and it is out for a Liverpool throw deep in their own half.
Free-kick on the right for United in a dangerous spot taken by Nani but the delivery is appalling again and goes out for a Liverpool throw on the other side of the pitch.
Nice ball down the right for Hernandez to chase but Enrique does well to get the better of the Mexican. The latter then has a shot from just outside the area but his effort has little power.
Great ball down the left to Welbeck from Carrick but awful control from the striker and the ball is out for a Liverpool throw.
Johnson still struggling after that tackle on Evra. He limps off and Andre Wisdom comes on in his place.
Great shot from Nani from just outside the box and Mignolet gets down very well to his left to save and force the ball well clear of the area.
Henderson loses out to Evra and he steams towards the Liverpool area but Johnson crunches into the tackle - fairly - and wins the ball. Evra walks gingerley away from the incident. Johnson also sore.
Van Persie loses out to Gerrard on halfway and the latter wins a free-kick as the Dutchman tries to win the ball back.
Valencia looks ready to come back on. Short backpass from Vidid causes a problem for De Gea, who has to hack the ball clear.
United kick the ball out on the right in their own half as Valencia continues to struggle with his eye problem. He is off to get treatment and Liverpool return the ball to United from the throw-in.
Corner on the right for United is delivered to the near post and a Giggs header is gathered by Mignolet.
Good strength down the left from Sturridge gets the better of Ferdinand. He passes inside but the return is way to strong and he gives the ball away.
Nani has a couple of chancesd to try and create something on the edge of the Liverpool area but the Reds are back in numbers and are soon able to clear.
Sterling passes to Enrique on the left and goes for the return but the ball is far too strong and goes behind for a United goal-kick.
Welbeck pops up on the left and feeds Young in the centre but his touch is too heavy and Henderson clears from his own area.
Welbeck wriggles between defenders in the United area and a slight nudge from Aspas sees him go down. Opposing views from both sides as to whether it is a penalty kick.
Good cross from the left by Young sees Aggeer and Mignolet clash with each other as they try to clear. The ball drops to Evra outside the box but his shot is pretty tame.
Lucas wins the ball well in midfield from Young and he quickly releases Sturridge. The latter can't real create anything and loses possession near the United box.
Much more lively in the opening stages of the half from United. Strong shoulder charge from Welbeck on Gerrard and a free-kick for the hosts taken by Agger from his own half.
Valencia released by Giggs down the right and he surges into the box under pressure from Enrique. The ball goes behind for a United corner but it is then cleared.
Giggs then takes a corner on the right and a weak header from Agger is met by Young. His shot is goalbound but hits Johnson and bounces clear of danger.
Carrick fouls Aspas and the former is given a last warning by the ref. The free-kick is delivered by Gerrard, Aspas misses it and Agger guides his attempted headre over the bar.
Aspas tries to find Sturridge in some space on the right but there is too much pace on the ball and it is out for a United throw deep in their own half.
Early cross from the left by Evra but it is easily intercepted by Skrtel. First corner of the second half now.
Matthew Brown says: "Hi David, I'm really disappointed with United, we have such a mediocre midfield, where on earth is Kagawa? Young and Cleverley need to take a hard look at themselves as they are not United standard, we need to buy a midfielder or we will get found out against the top 5 without a shadow of a doubt, buy Moyes, buy."
Liverpool go into the break a goal up and they are 4/9 at Sky Bet to keep their noses in front. Man United are 8/1 for the win with the draw a 3/1 chance.
Great time to have a bet on the second half! Here are some Price Boosts from Sky Bet: Liverpool to win 3-0 14/1, Manchester Utd to win 3-1 50/1, Steven Gerrard to score next 14/1 and Robin Van Persie to score next 13/2.
Chris Boucher says: "Well from this half & the full game against Chelsea so far Cleverly & Wellbeck are way below United quality. Not sure how much confidence England fans should have in them going forward! Very very poor!"
Probably not a bad time for the whistle to go as tempers become a bit frayed. The ref has a few words with the two captains to try and keep a lid on things. See you in 15!
Young crosses from the right but it evades everyone. A few choice words between Gerrard and van Persie after the latter gives Skrtel a shove in the penalty area.
Attempted through ball from Giggs tries to pick out van Persie but the pair are not quite on the same page.
Good play from Coutinho and Lucas on the edge of the United area. The latter shapes to shoot but attempts to feed Sturridge in the box but his pass is not accurate enough.
Good cross from the left by Young is just over the head of Welbeck and is cleared. Carrick drags down Aspas as he tries to break and that is the fourth yellow card of the game.
Nice break down the right by van Persie but he is crowded out and loses possession. The Dutchman is frustrated and leaves a foot in on Agger in an attempt to get it back and he is another name to go in the book.
Johnson battles his way down the right and leaves Carrick and Evra in his wake on the floor - whistle goes for a United free-kick.
We finally get around to the free-kick being taken but it is a poor one from Coutinho and goes well over the bar.
Jones hobbles off for now as Aspas goes in the book as well for gesturing for Cleverley to be booked. The irony!
Jones down in midfield but Liverpool play on. Cleverley not happy and he hacks down Coutinho on the edge of the United box. Cleverley goes in the book
Van Persie gets into a good position to cross on the left but there is no United player in the box to meet his centre.
Nice play down the right by Henderson and his cross is aimed towards Sturridge deep in the United area but Phil Jones does well to get up and head clear.
A couple of hefty challenges just outside the United area lead to a Liverpool free-kick. Gerrard takes and his effort is saved down low to his right by Mignolet.
Johnson surges down the right channel towards the United penalty area and he passes square to iago Aspas but the latter loses control and the attack breaks down.
Long ball through from the back down the right flank gives Jordan Henderson something to chase but it is a bit too strong and goes behind for a United goal-kick.
Welbeck squeezes a nice pass through to Tom Cleverley in the Liverpool box but it just gets stuck under his feet a little and Enrique can clear.
Hefty joint challenge from Giggs and van Persie on Coutinho as the young midfielder ties the veteran Welshman in knots.
Welbeck tries to weave himself into a shooting position in the Liverpool box but a great challenge from Glen Johnson stops him getting a shot away.
Some slick passing from United but Michael Carrick's attempted through ball is cut out by Martin Skrtel.
Welbeck surges forward towards the Liverpool area but Steven Gerrard tracks back well and gets in a good tackle to claim the ball.
The free-kick is delivered into the box and eventually goes behind for a United corner. The corner goes right through to van Persie but it is a yard behind him and he can't get the ball under control three yards out.
Left-foot shot from Danny Welbeck from just outside the Liverpool area is pretty tame and easily gathered by Mignolet.
Throw to United deep in the Liverpool half after Jose Enrique blocks an attempted cross by Phil Jones.
First attempt in the game from Philippe Coutinho but his effort from just outside the box is dragged left of the target.
Free-kick on the right for United in a threatening area taken by Giggs. Patrice Evra is allowed to head it back into the six-yard box where Robin van Persie sends the ball over the bar with an overhead attempt.
The corner is swung in and Daniel Agger heads goalward - Sturridge gets the final touch with his head from close range to send the ball into the roof of the United net.
Daniel Sturridge has his first sight of goal but his attempt takes a deflection of Rio Ferdinand for a corner.
Swift early attack from United down the left and the ball is centred. It reaches Ryan Giggs at the far post and his centre is caught by Simon Mignolet.
Just over five minutes to kick-off - many thanks for all your emails and thoughts and sorry I couldn't get around to them all. Here's hoping for a fantastic game!
Tarek Rahman says: "Super Sunday starts too early for those who had a super Saturday night! That said, now that I'm awake I can't wait for this match! I'm fuming that Kagawa isn't playing, what the hell is Moyes playing at?! The Dortmund fans are furious and want him back, so why the hell are we not playing him if the Champions league finalists want him in their first team?! Old man Giggs, the flop Ashley Young and Cleverley who seems to be allergic to anything that sends the ball an inch forward are going to ruin this for United. A very pessimistic United fan predicting 2-1 to Liverpool."
"Hi Will from benidorm here on me hols but watching match very disappointed Kagawa not playing but never the less utd win for me 2-1."
Manchester United: De Gea, Jones, Ferdinand, Vidic, Evra, Carrick, Cleverley, Young, Giggs, Welbeck, van Persie Subs: Anderson, Smalling, Lindegaard, Hernandez, Nani, Valencia, Buttner.
Liverpool: Mignolet, Johnson, Skrtel, Agger, Jose Enrique, Gerrard, Lucas, Henderson, Aspas, Coutinho, Sturridge Subs: Brad Jones, Alberto, Sterling, Ibe, Kelly, Flanagan, Wisdom.
Here are some Sky Bet Price Boosts: Liverpool to win 2-0 14/1, Manchester Utd to win 2-0 18/1 Daniel Sturridge to score first 9/1 and Robin Van Persie to score first 11/2.
Henry Futcher says: "i'm an Everton fan so am in an awkward situation with Liverpool being rivals and Moyes now at Man.Utd... Hopefully a drab 0-0. But I'll go for a 2-0 Man.U with Van Persie and Welbeck scoring."
A quick update on the Rooney injury - he has suffered a cut on his forehead and will have "no chance" of featuring for England in their forthcoming World Cup qualifiers, manager David Moyes has said.
Oscarthegrouch says: "When Rooney was ruled out I hoped Kagawa would get his chance, the lad has good vision and an eye for goal. But no, Moyes goes with the ineffective Cleverley, who must think a forward pass or a shot at goal warrants a red card, and old man Giggs, who despite being a legend, needs to realise that time has caught up with him and should retire from playing to concentrate on coaching. He's actually blocking the path for the young talent like Januzaj, Powell and Petrucci to make a claim for a first team place."
Reece Buckby in a similar vein: "What has kagawa gotta do to get a game I believe he has that something we will need today to win but I can rvp banging in another goal."
Dan Rabey has a strong opinion: "Moyes in my opinion is a moron not giving Kagawa a start today. Either that or Kagawa is already on his way out... I mean seriously what is Moyes playing at."
Darren is not in the most energetic mood today: "Hi as a neutral I'd go for a boring 0-0 or a tight 1-0 either way, i can't see any other result considering David (I'm a bore) Moyes is in charge at man utd."
Ayeshi Poli says: "One of the firiest games of the season - As a Liverpool Fan I am predicting a 2-1 win to Liverpool... Can not wait to see the atmosphere at Anfield. No Rooney for utd - that surely can't be there excuse for not winning right? Lets bring it on!"
Kevin Hall says: "Still early days but expect both teams to be in top gear unlike Man City's unsynchronised form. Liverpool have a limited range of penetrative play as seen these last 3 seasons and Man Utd will not be extended to defend. One would anticipate enough service from Utd's midfield and overlapping defenders to create more chances than the hosts and win. If Liverpool stack the defence we may see a goalless result but tip 1-0 Utd."
Bill Blewitt: says: "As a neutral I hope for a great game, as a Geordie, I do NOT want Man Utd to get a point. But I think result will be 2-1 Man Utd, despite my best wishes."
Here is the pre-match team news: Wayne Rooney is missing for Manchester United. Rooney was injured in training yesterday and not fit enough to even travel to Merseyside, with his place going to Ryan Giggs as Ashley Young is also included in preference to Antonio Valencia. Liverpool are in the rare recent position of lording it over their fierce north-west rivals, following the back-to-back wins over Stoke and Aston Villa, although manager Brendan Rodgers is forced into a change as Martin Skrtel replaces Kolo Toure, who has a groin injury.
Tony Purcell says: "Greetings from Sunny Brisbane.....I think Uniteds attack will be the difference, United 15 goals and 28 points more last season, already 4 goals to 2 scored this term......going big....4-2 to united....RVP hat trick...."
Paul Dingley writes: "This game is going to be fantastic! If Liverpool win that will put us at the top of the league and I hope that Arsenal can beat Spurs. Hope that Sturridge is on fire - like he has been since he joined and that's job done.........simples!!!"
Thanks to Conor Sheridan, who says: "I hope kagawa plays, if wisdom is playing centre, the speed & intelligence kagawa has will be too much for him & then RVP can do what he does best,score but I hope welbeck continues to show his good form today, it will really prove his doubters wrong, I'm saying 1-3 united, come on!"
Daniel Miller says: "I predict that liverpool are going to get a 2-1 win today because they're in front the kop so they're motivated. I also think that Daniel Sturridge may cause a few problems for the Manchester IUnited defence. But hopefully van persie gets my some fantasy football points."
Thanks to Craig Blakemore: "As a Man U fan I'm concerned about Sturridge as he seems to be in top form at the moment. No Rooney is a blow to United. I'm going for a 2 - 2 draw, RVP & Sturridge both scoring for their teams."
Sayed says: "Hi there Liverpool might get more of the ball possession but the don't have good finishers. I think united will edge past Liverpool 2-1. Shinji and rvp on target."
Tom from Norwich says: "As an unbiased neutral I can see a tight but entertaining match with RVP being the difference, 2-1 to Utd."
Thanks to Christoper, who says: "Hello there david, Christopher from sunny Barcelona here, enjoying my holiday but keeping and eye on this match, I'm an Everton supporter so hoping for a Man U win but also fantasy points at stake, going for a tight game 1-0 to Man U Valencia to get the goal."
A cracking contest in store at Anfield and Sky Bet go 6/4 for a Liverpool win with United 15/8. The draw is on offer at 12/5 - what a game to have a punt on!
Finley Jack adds: "Very close game today, I feel that the inexperience of Liverpool attack could be a major factor in the game. 2-1 united for me."
Gabriel Sutton says: "I'll put my neck on the line and go for Liverpool here. Out of United's last 5 visits to Anfield, Liverpool have taken 10 points which tells you how much they want to win these games. With David Moyes in charge of Man U and Liverpool having won their first 2, they'll never have wanted to beat United more. If as reports say Wisdom is playing at centre-back RVP will probably score, but Liverpool have got a lot of small, tricky players who have the pace to potentially cause Ferdinand and Vidic problems. 2-1 to Liverpool."
Ali from Bournemouth says: "This game gets bigger every season, David Moyes will be really wanting to win at Anfield for the first time and Mr Rodgers will want to get one back on united from last season, if Liverpool play there great football and moyes gets it wrong at anfield again then we should be on for a home win."
Jospeh Ng says: "It's certainly good news for Liverpool that Rooney is out. At least we'll have only RVP to contend with. I am really hoping for a SUPER defensive performance from our full-backs tonight! Being a Pools fan, I am going for a 2-1 win over the Red Devils!!"
Hello again to Chris Green, one of our emailers from yesterday: "I really hope the Red Devils come out on top today and beat our local rivals, Liverpool, as it's always a nice feeling when your team wins in a local derby. However, this match won't be easy for United by any stretch of the imaginations because Liverpool have a good home record; this is the reason why many teams struggle to get a result at Anfield nowadays. So, United will need to be at their best if they are to claim the bragging rights in today's match, or this could be a long afternoon for the Red Devils' defence."