Real Sociedad pulled clear of the La Liga relegation zone with a 2-0 win over Sevilla.
Valencia hit five to beat high-flying Celta Vigo, while Eibar continued their rise up La Liga with victory over Getafe.
Atletico Madrid missed the chance to climb to the top of La Liga after drawing 1-1 with Deportivo on Friday night.
Atletico Madrid are ready to challenge for La Liga title this season, according to manager Diego Simeone.
Sevilla thrashed Getafe 5-0 in La Liga on Saturday night, while Granada drew with Real Betis and Malaga saw off Deportivo.
Barcelona and Real Madrid will start their Copa del Rey campaigns against third-tier clubs.
A hat-trick from Brazilian striker Charles saw Malaga beat David Moyes' Real Sociedad 3-1 and get off the winning mark this season.
In his live Q&A, Sky Sports Guillem Balague said there is no interest from Barcelona in Liverpool's Philippe Coutinho.
David Moyes' Real Sociedad were held to a 0-0 draw in the Basque derby by Athletic Bilbao, while Deportivo moved up to sixth.
Rafael van der Vaart's long-awaited debut lasted just 48 minutes as Real Betis were beaten 2-1 at home by Deportivo.
Villarreal defeated Athletic Bilbao to remain joint-second with Real Madrid and Celta Vigo.
Federico Cartabia scored his first-ever goal for Deportivo La Coruna on Thursday and it was a memorable strike too…
Lucas Perez wrapped up a 3-1 victory for Deportivo la Coruna over 10-man Rayo Vallecano on Monday.
Former Newcastle midfielder Jonas Gutierrez is set to join Deportivo La Coruna on a free transfer, subject to a medical.
Jackson Martinez came off the bench to score his first Atletico Madridgoal in a 3-0 La Liga win over Sevilla at the Ramon Sanchez Pizjuan.
Jon Driscoll is joined by Terry Gibson to discuss the weekend's action, while Guillem Balague speaks with Arsenal's Mikel Arteta.
Espanyol got their La Liga campaign off to a perfect start, while Deportivo and Real Sociedad played out a goalless draw.
Juan Carlos Valeron is back in La Liga at 40. Find out why he'll be applauded everywhere he goes.
Sky Sports will remain the home of La Liga for another three seasons thanks to a new broadcast agreement announced today.
Deportivo La Coruna have agreed a deal to sign Watford right-back Juanfran on loan for another season.