Guingamp picked up their first points of the Ligue 1 season as they shocked Marseille 2-0 at the Stade du Roudourou.
There was defeat in Ligue 1 for Lyon, while Monaco came from behind to secure a 1-1 draw with Toulouse.
Monaco secured a comeback victory in their Ligue 1 opener, but there was defeat for Marseille before manager Marcelo Bielsa resigned.
Monaco sealed a spot in the Champions League thanks to a 1-0 win at Lorient in the final round of Ligue 1 matches.
Liverpool give U21s more game time than Premier League rivals but top flight lags behind Europe.
St Etienne beat Guingamp 2-1 but it was not enough to propel them into the Champions League.