Davy Klaassen scored twice as Ajax Amsterdam trounced SC Cambuur 5-1 to extend their lead at the top of the Eredivisie.
Heracles missed the chance to close the gap on Eredivisie leaders Ajax as they conceded a 90th-minute equaliser at PEC Zwolle.
Feyenoord lost ground in the Eredivisie title race after a shock 1-0 loss against ADO Den Haag.
PSV Eindhoven and Heracles maintained their pressure on the Eredivisie's top two with late away wins on Saturday.
Dwight Lodeweges has stepped down as head coach of Dutch club SC Heerenveen after a disappointing start to the season.
Heracles moved to within a point of Eredivisie leaders Ajax after a 2-0 win at home to Heerenveen.
There were Eredivisie wins for both Ajax and PSV on Saturday, while second-placed Heracles slipped to defeat.
Wout Weghorst scored the only goal as high-flying Heracles beat ADO Den Haag 1-0 to climb to second in the Eredivisie.
Swansea have signed five-cap Sweden goalkeeper Kristoffer Nordfeldt to compete with Lukasz Fabianski for the No 1 spot.
Vitesse beat Heerenveen 5-2 as they claimed a Europa League place with a 7-4 aggregate win in the post-season play-offs.
AZ claim a Europa League place at the expense of Feyenoord, who were consigned to the play-offs for a place in Europe.
NAC Breda face a relegation play-off, while Manchester United-bound Memphis Depay scored for PSV.
PSV came from behind to extend their lead at the top of the Eredivisie standings, while there were wins for Heracles and Utrecht
Champions Ajax delayed PSV's impending Eredivisie title win for another week as they won 2-0 away at Heracles Almelo.
Five-star PSV close in on Dutch title after comprehensive victory at FC Twente, while Heracles grab dramatic late win
Markus Henriksen netted a late winner as AZ strengthened their grip on fourth place with a 2-1 win over Cambuur Leeuwarden.
Defender Nicolas Isimat-Mirin scored a rare goal to hand leaders PSV a nervy 2-1 home win over Groningen.
Heerenveen's Mark Uth produced one of the misses of the season during Sunday's Eredivisie clash with Ajax.
Ajax staged a late rally to beat PSV Eindhoven 3-1 on Sunday to give their faint title hopes a boost.
Ricardo Kishna struck twice as Ajax beat Twente 4-2 in the Eredivisie to cut PSV's Eredivisie lead back to 12 points.