Bayer Leverkusen, CSKA Moscow, BATE and Astana all reached the Champions League group stages on Wednesday night.
Serie A champions Juventus saw their 47-match unbeaten home league record come to an end against Udinese.
Differing fortunes for Rome rivals as Lazio beat Bologna and Roma are held by Verona on Serie A's opening day.
With Gazza set to appear on Soccer AM this weekend, we look back at his most iconic moments.
Keita Balde came off the bench to score the winner as Lazio beat Bayer Leverkusen 1-0 at the Stadio Olimpico in Rome.
New signings Mario Mandzukic and Paulo Dybala scored as Juventus beat Lazio 2-0 to win the Italian Supercoppa in Shanghai.
Lazio coach Stefano Pioli has extended his contract with the Serie A side.
Lazio president Claudio Lotito's home raided by authorities as part of an investigation into allegations of attempted extortion.
Lazio forward Miroslav Klose has not ruled out reversing his decision to retire from international football.
Lazio have ruled out a move for Manchester United forward Robin van Persie, saying he is "outside of their parameters".
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Rafael Benitez failed to deliver Champions League football to Napoli as his final act before leaving ended in a 4-2 loss to Lazio.
Rafael Benitez failed to deliver Champions League football to Napoli as his final act before leaving as Lazio won 4-2.
Roma booked their place in the group stage of next season's Champions League with a dramatic 2-1 derby win over Lazio.
Liverpool give U21s more game time than Premier League rivals but top flight lags behind Europe.
Going into the final weekend of the season in La Liga, Bundesliga and Ligue 1, we look at the potential gains and losses.
Juventus won the Coppa Italia thanks to Alessandro Matri's extra-time strike which secured a 2-1 victory over Lazio in Rome.
Italian champions Juventus can set up a shot at the treble with Coppa Italia win on Wednesday.
Lazio are potentially just one win away from booking their place in the Champions League after beating Sampdoria 1-0.
Inter Milan are in danger of missing out on a European place after goalkeeper Samir Handanovic gifted champions Juventus a 2-1 victory.