Bayern Munich ensured they will finish atop Group F in the Champions League with a 4-0 thrashing of Olympiakos.
Real Sociedad pulled clear of the La Liga relegation zone with a 2-0 win over Sevilla.
Which team has recorded the best win percentage in the history of six of Europe's leading leagues? Find out here...
Valencia hit five to beat high-flying Celta Vigo, while Eibar continued their rise up La Liga with victory over Getafe.
Head coach Nuno said he was "ashamed" of Valencia's display after they were beaten 1-0 by Gent in the Champions League.
Neymar? Sergio Ramos? Inaki Williams? Take a look at three potential La Liga goal of the season contenders from over the weekend.
Barcelona beat BATE Borisov to close in on the Champions League's last 16, while Zenit are through and Olympiakos, Roma and Porto also won.
Atletico Madrid beat Valencia 2-1 on Sunday while David Moyes' Real Sociedad cruised past Levante 4-0.
Phil Neville is loving life so much in Valencia that he cannot see himself returning home any time soon.
Take a look at the five best goals from this weekend's La Liga action, including Luis Suarez and Alen Halilovic.
Substitute Ivan Rakitic scored both goals as Barcelona sealed a comfortable 2-0 win over BATE Borisov.
Sevilla came from behind to salvage a point at Eibar but their unconvincing away form continues.
Barcelona and Real Madrid will start their Copa del Rey campaigns against third-tier clubs.
Villarreal remain the early pacesetters in La Liga despite suffering their first defeat of the season against neighbours Levante.
In his live Q&A, Sky Sports Guillem Balague said there is no interest from Barcelona in Liverpool's Philippe Coutinho.
A look at this week's best goals from across the globe, starring Alexis Sanchez, Dani Parejo and Lewis McGugan.
Barcelona beat Bayer Leverkusen 2-1 on Tuesday, while there were also Champions League wins for Bayern Munich and Valencia.
How have Villarreal got to the top of La Liga? How will Lionel Messi's injury affect the title race? Guillem Balague has the answers...
Valencia secured a much-needed 1-0 win over Granada in La Liga on Friday - their first home victory of the season.
Imanol Agirretxe's hat-trick helped Real Sociedad beat Granada 3-0 and ease the pressure on boss David Moyes.