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Brothers John and Jim Harbaugh go up against each other in Super Bowl XLVII between Baltimore Ravens and San Francisco 49ers.
The respective head coaches will be trying to claim not only the Vince Lombardi trophy but also family bragging rights in New Orleans.
In honour of the Harbaughs, we have put together a list of the top 10 sporting brothers.
Narrowing the entries was tough as there have been plenty of talented families to leave their mark in the sporting world over the years.
You can send in your own suggestions using the feedback form at the bottom of the page.
The coal-mining village of Ashington in Northumberland provided two members of England's only World Cup winning team, Jack and Bobby Charlton.
Jack, the elder by more than two years, was a central defender for more than 20 years with Leeds United, while Bobby's goal-scoring exploits made him a Manchester United legend.
But the high point of their respective careers came in the summer of 1966 when both were integral members of England's charge to the Jules Rimet Trophy.
The Nevilles - Gary, Phil and Tracey - are another remarkable set of sporting siblings from the north of England.
The eldest, Gary, has been a mainstay of the trophy-laden Alex Ferguson era at Manchester United and is England's most capped right-back.
Phil, initially alongside Gary at Old Trafford and more recently as captain of Everton, has also carved out a successful career at the top level, including 59 England appearances.
Phil's twin sister Tracey won 74 caps for England at netball.
Cricket in general and Australian cricket in particular has seen many brothers ply their trade at the top level.
Arguably the cream of the crop are the Chappells - Ian, Greg and Trevor.
The middle brother Greg was the best player, an elegant right-hander who finished his 87-cap Test career with an average of 53.86.
Ian, the eldest, was also a batsman of repute, collecting more than 5,000 Test runs and building a successful team in his own tough image during his time as Australia captain from 1971-75.
Trevor, unfortunately, is best remembered for his under arm delivery at the end of a one-dayer against New Zealand, denying the Kiwis the chance to tie the match with a six. He was acting on the instructions of Greg, Australia's captain that day.
The controversy somewhat overshadowed his own international career as an all-rounder, which consisted of three Tests and 20 one-dayers.
Fast-forward a couple of generations and there was another set of brothers in Australia's Test team.
The Waugh twins, Steve and Mark, combined for 296 Test appearances and almost 19,000 runs in Australia's all-conquering line-up. Steve captained his country with great success from 1998-2004.
They once put on 464 for the fifth wicket for New South Wales in the Sheffield Shield but their early forays in international cricket did not always promote family harmony - Mark made his Test debut in 1991 at the expense of Steve.
Dean Waugh, four years younger, also made one first-class appearance, while Danny - the youngest of the four Waugh brothers - played in the Sydney grade competition.
The Klitschkos are the first brothers to simultaneously hold versions of the world heavyweight title.
Vitali, the oldest by almost five years, is the reigning WBC champion, while Wladimir owns the IBF, WBA and WBO belts.
There is, however, bad news for those who would like to see the heavyweight division unified as the Klitschkos have ruled out facing each other in the ring.
The Schumachers are the most successful brothers to have graced Formula One.
Michael ranks as one of the greats of the sport, having won seven world titles for Benetton and Ferrari in the decade from 1994.
His younger brother Ralf suffers in comparison but nevertheless managed six grand prix victories in a career that included spells with Jordan, Williams and Toyota.
For a time in the mid-90s playing on the wing for England was the exclusive preserve of the Underwood brothers, Rory and Tony.
Rory even switched flanks from right to left to accommodate his younger brother Tony in the team.
They played together through to Rory's retirement in 1996, by which point he had bagged a record 89 caps and 49 tries for England.
Tony's career did not quite hit the same heights, he scored 13 tries in 29 Tests but is perhaps most famous for being trampled on by Jonah Lomu to provide the defining image of England's 1995 World Cup semi-final mauling at the hands of New Zealand.
Peyton and Eli Manning are the first brothers to each quarterback a team to Super Bowl glory.
The sons of former Saints signal caller Archie Manning, they have won three Super Bowls between them.
Peyton, the older by almost seven years, guided the Indianapolis Colts to a 29-17 victory over the Chicago Bears in 2007, followed 12 months later by Eli overseeing the New York Giants' 17-14 success over the New England Patriots.
And Eli repeated the trick in 2012, guiding the Giants to a repeat win over the Patriots.
The Laudrup brothers, Michael and Brian, are another fine example from the world of football.
Michael was a crowd-pleasing midfielder throughout a career that included stops at Juventus, Lazio, Barcelona and Real Madrid.
He was also part of the "Danish Dynamite" team that reached the last 16 of the World Cup in 1986 - and also the quarter-finals 12 years later.
Brian, the younger brother by five-and-a-half years, starred on the wing in the Rangers team that dominated the Scottish league in the 1990s, although he also had a brief and unsuccessful spell with Chelsea.
He won the European Championship with Denmark in 1992 and featured alongside Michael at the 1998 World Cup.
The Turin-born brothers have been made their mark on golf's European Tour with five victories between them.
Francesco has enjoyed the more consistent career, with his finest hour coming in 2010 when he won the lucrative WGC-HSBC Champions event.
They made their Ryder Cup debuts together in Europe's victory at Celtic Manor in 2010 after Edoardo convinced skipper Colin Montgomerie to pick him as a wild-card (Francesco qualified) by winning the final counting event, the Johnnie Walker Championship at Gleneagles.
No Italian has won a major championship - Costantino Rocca coming closest when he lost a play-off to John Daly at the 1995 Open - a statistic the Molinaris will be striving to change in the coming years.
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