Keita Balde stepped off the bench to clinch Lazio a 2-1 win at relegation-threatened Empoli and lift them up to fifth in the Serie A table.
Suso struck an 85th-minute equaliser as AC Milan drew 1-1 at Lazio in Serie A on Monday night.
Juan Cuadrado's thunderbolt gave Juventus 1-0 home win over Inter Milan on Sunday, as Sampdoria beat AC Milan and Lazio hit six.
Queens Park Rangers have completed the loan signing of Ravel Morrison from Lazio until the end of the season.
Gonzalo Higuain reached 15 goals for the Serie A season as Juventus reinforced their position as leaders with a 2-0 win over Sassuolo.
In-form Inter Milan moved up to fourth in Serie A with a 3-0 success at home to bottom-of-the-table Pescara on Saturday.