Substitute Nicolas de Preville salvaged a point for Lille in a 1-1 draw with St Etienne at Stade Pierre-Mauroy on Friday.
Julian Draxler scored on his PSG debut as the defending Coupe de France champions beat Bastia 7-0 to advance to the last 32.
Monaco moved back to the top of Ligue 1 on goal difference after a late strike from Frederic Sammaritano earned Dijon a 1-1 draw.
Monaco kept up their outstanding recent form as Valere Germain scored twice in a 4-0 win over Marseille on Saturday.
Radamel Falcao was on target as Monaco went top of Ligue 1 with a 3-0 win at bottom side Lorient while Lyon went fourth.
Monaco trimmed Nice's lead at the top of Ligue 1 to three points as Leonardo Jardim's side thrashed Nancy 6-0.
Lyon's alarming slump in form continued on Saturday as they lost 3-1 at home to Guingamp.
Paris Saint-Germain claimed a share of second place in Ligue 1 with a 2-1 win at Nancy.
Monaco defender Djibril Sidibe has revealed he rejected a move to Arsenal in the summer over concerns about making the first team.
Monaco thrashed 10-man Metz 7-0, while there were wins for Lille, Caen, Nantes and PSG in Ligue 1 on Saturday.
Alassane Plea's goal earned Nice a 1-0 win over AS Nancy on Sunday that moves them top of Ligue 1.
Reigning champions Paris Saint-Germain cruised to a 3-0 win over Dijon which moves them top of Ligue 1.
Thomas Lemar fired a late double as Monaco moved three points clear of PSG at the top of Ligue 1 with a 3-0 win against Rennes.
Monaco returned to the top of the Ligue 1 table thanks to a thumping 4-1 win in Lille on Saturday.
Southampton have confirmed the signing of Lille winger Sofiane Boufal and Sky sources understand the fee to be a club-record £16m.
Patrick Kluivert will be picking his #One2Eleven on The Fantasy Football Club on Friday evening, and you could win his team sheet.
Alexandre Lacazette was forced off with a knee injury as Lyon slipped up to Dijon, while Nice were held by Lille.
Southampton have agreed a club-record £21m fee for Lille striker Sofiane Boufal, according to sources at the south-coast club.
Gabriel Boschilia's strike gave Monaco a 1-0 win at Nantes on Saturday.
Bordeaux beat Saint-Etienne, while newly-promoted Metz came from behind to beat Lille. Get the latest from Ligue 1...