Overseas signing Martin Guptill smashed a quickfire 72 as Derbyshire eased to a six-wicket victory in their Friends Life t20 North Group fixture with Warwickshire.
The New Zealand batsman cracked six sixes in his 44-ball knock as the Falcons chased down their 137-4 target with seven balls to spare on Sunday afternoon.
The contribution was Guptill's highest for his new county and puts Derbyshire back on course to claim a quarter-final berth.
Guptill's strokeplay helped the Falcons pass 50 in the eighth over before the Bears claimed the breakthrough.
Durston was lbw to Steffan Piolet for 22 and although Chesney Hughes went cheaply to the former Derbyshire spinner Ant Botha, Guptill made sure nothing would disrupt the Falcons' flight.
After reaching his half-century from 34 balls, the Kiwi pressed on the accelerator in the 14th over by pulling Piolet for two consecutive sixes.
While he then pulled Darren Maddy's first ball to wide long on, the damage had been done long before Ross Whiteley drove Barker for the winning boundary.
Earlier, Warwickshire limped to just 137-4 despite a breezy half-century from Jim Troughton (55 not out from 41 balls).
The Bears, who were without Ian Bell, Jonathan Trott and Chris Woakes, lost three wickets in the first six overs.
Neil Carter was stumped charging Wes Durston, Varun Chopra was run out going for a second and Jonathan Clare clung onto a fierce return catch to remove Will Porterfield.
Another wicket then would have seriously undermined the Bears but Troughton made the most of his let-offs to dominate the rest of the innings.
He added 48 in seven overs with Maddy, who was stumped for 21 going for a big drive at Chesney Hughes, and reached his 50 by driving Steffan Jones for his second six.
Ex-Derbyshire skipper Rikki Clarke also cleared the ropes in his unbeaten 25 from 22 balls and his unbroken stand of 56 with Troughton at least gave the Bears a respectable total although it looked, and proved, at least 20 runs short.