Steve Harmison claimed his county-best figures of 7-29 to bowl Durham to a 219-run triumph on the final morning against Warwickshire at Emirates Durham ICG.
Resuming on 111-3 in pursuit of 354 for victory, the Bears suffered a spectacular collapse to be bowled out for 134 in under 10.2 overs.
Harmison was the destroyer in chief with six of the final seven wickets, including three in an over.
The fast bowler, out of favour with England since the final Test of last summer's Ashes, had Ateeq Javid (30) lbw in the second over of the day to end a fourth-wicket alliance of 68 with Jim Troughton.
Mitchell Claydon (3-47) bowled Troughton (43) but thereafter it was the Harmison show.
He accounted for Tim Ambrose for a duck and then, in his next over, removed Neil Carter (3), Boyd Rankin (0) and Imran Tahir (0) in the space of five deliveries.
Harmison completed the rout by adding the scalp of last man Andrew Miller (4), leaving number seven Rikki Clarke on eight not out.
Durham, the two-time defending champions, have climbed two places in the Division One table to fifth, while Warwickshire's sixth defeat of the season has left them firmly in the relegation mire.
Meanwhile, Harmison's haul took him past 700 first-class wickets, of which 423 have been for Durham. Having missed four of their previous seven games this season with back and ankle injuries, he had only nine championship wickets going into this match.
Imran Tahir bowled Warwickshire back into contention in their LV County Championship Division One clash with Durham.
The Bears will resume the final day of the Division One fixture at Emirates Durham ICG on 111-3 after being set a target of 354 for victory.
An unbroken stand of 65 between Jim Troughton and 18-year-old Ateeq Javid raised hopes that the visitors could pull off an unlikely victory on their travels.
The duo had come together with their team in some trouble at 46-3 but teenager Javid looked secure in making an unbeaten 30 alongside Troughton, who was on 38 not out at the close of play.
Tahir had made sure Durham didn't get too far ahead by picking up 6-69 to bowl out the home side for 289 in their second innings.
The leg spinner, who picked up an eight-wicket haul against the same county at Edgbaston earlier in the summer, ended an opening stand of 158 when he had Michael Stoneman leg before for 60.
From then on Durham collapsed, Michael Di Venuto departing for 92 before Tahir rattled through the tail, taking four of the last five wickets to fall.
Warwickshire all-rounder Rikki Clarke kept his side in with a fighting chance of victory, but Durham remain in control after day two at Emirates Durham ICG.
Replying to the reigning champions' first-innings 288, Warwickshire slumped to 115-5 before Clarke's battling 68 kept them in touch.
The visitors clawed up to 224 all out, however Durham extended their lead to 142 after openers Mark Stoneman (42 not out) and Michael Di Venuto (31no) safely negotiated a tricky late session to reach 78-0 at the close.
England reject Steve Harmison (2-45) dismissed Warwickshire openers Ian Westwood and Darren Maddy during a lively opening burst.
But it was his new-ball partner Callum Thorp who wreaked most havoc, the Australian running through the Bears' lower order to finish with figures of 4-54.
Clarke, batting at number seven, was waging a lone battle, but found an unlikely allay in number 11 Boyd Rankin. The pair added 55 for the final wicket - Rankin contributing just 10 - as Warwickshire registered their first batting bonus point in five games.
But Stoneman and Di Venuto kept Durham firmly in control with an unbroken 78-run stand to end an eventful second day.
Ian Blackwell spared Durham's blushes with his 86 helping them to a half-decent total of 288 in their first innings against Warwickshire.
The champions were reduced to 112-5 before Blackwell came in and, despite riding his luck at times, compiled his 147-ball knock.
The ball swung in the morning, but there was also enough in the pitch to encourage the bowlers to bang a few in and Gordon Muchall, Ben Stokes and Chris Rushworth all fell when pulling, while Neil Carter found extra bounce to have Mark Stoneman taken at second slip.
Dale Benkenstein joined Muchall at 21-2 and while the senior man dug in his partner made 27 before his top-edged pull off Rikki Clarke was athletically held by Boyd Rankin.
Benkenstein made 10 before he pushed forward to the perfect away swinger from Darren Maddy and edged to Ambrose. Bad light ended play nine overs from the end.