England will welcome back Kevin Pietersen, Joe Root and Jonathan Trott for Friday's opening one-dayer against Australia at Headingley on Friday.
The batting trio return to bolster a top order that struggled in Tuesday's win over Ireland, leaving the experienced pairing of Eoin Morgan and Ravi Bopara to eventually steer England home with a world record fifth-wicket stand.
James Taylor and Gary Ballance, who managed 25 and a second-ball duck respectively in Malahide, will both drop out but Michael Carberry is likely to keep his place for the clash, which will be shown live on Sky Sports 2 HD.
The Hampshire opener has enjoyed a tremendously successful limited-overs season in domestic cricket but managed only 10 runs from 13 deliveries against the Irish. He also dropped two catches in the field, making it a tough ODI debut for the left-hander.
However Eoin Morgan - who will lead England in the five-match series in the absence of the rested Alastair Cook - insists Carberry will be better for the experience.
"Carbs is a very experienced cricketer," Morgan - who made an unbeaten 124 against his former team-mates in Dublin - said. "He will pick himself up, re-evaluate where he is at and we will encourage him to play with the freedom he does at Hampshire.
"We have very strong belief in him as an opening batsman."
Luke Wright opened with Carberry but it seems England will use Pietersen at the top of the order, a role he filled with great success against Pakistan in the United Arab Emirates in 2012.
With Trott and Root set to go in front of Morgan and Bopara and with Jos Buttler the established wicketkeeper, England's major selection issue is over the make-up of their bowling unit.
Steve Finn and Boyd Rankin, who took four wickets on his one-day debut for England, look certain to be the new-ball pairing considering there is no James Anderson, Stuart Broad or Tim Bresnan in the squad.
The hosts could hand a debut to Sussex's Chris Jordan or Somerset's Jamie Overton to add a third frontline seamer, though Ben Stokes filled that job in Ireland and with him at No 8 the batting is lengthened considerably.
Australia, meanwhile, warmed up with a crushing 200-run triumph over Scotland, Aaron Finch and Shaun Marsh both hitting big hundreds at the Grange to cement themselves as the opening combination.
Michael Clarke captains the tourists again after sitting out the two Twenty20 Internationals last week, while Fawad Ahmed looks likely to be the only frontline spinner selected.
With injured duo Ryan Harris and Mitchell Starc having returned home, Mitchell Johnson will lead the attack. The left-armer took four Scottish wickets in Edinburgh when he opened up alongside the experienced Clint McKay.
The biggest issue for both sides could be the weather - rain is forecast to fall for much of Friday in Leeds.