Half-centuries from Ian Cockbain and Alex Gidman powered Gloucestershire to a seven-wicket success over Derbyshire at Bristol.
Resuming at 19-1 in pursuit of a target of 146, the hosts lost Richard Coughtrie and Chris Taylor early on the final morning to slump to 34-3.
Derbyshire seamer Tim Groenewald (2-25) bowled Coughtrie for one and new-ball partner Tony Palladino (1-35) followed up with the scalp of Taylor (4), caught by Dan Redfern.
But rookie opener Cockbain and captain Gidman steadied the ship to reach lunch at 107-3, just 39 short of victory.
And the fourth-wicket pair knocked the remaining runs off in early afternoon in a partnership worth 112.
Cockbain, making his first-class debut, finished on 59 not out, while Gidman took a more aggressive approach in his unbeaten 70 from 75 balls, which featured 11 fours.
Greg Smith cracked a much-needed century, however Gloucestershire remain firm favourites to overcome Derbyshire at Bristol.
Following on, the South African all-rounder posted a fluent 130 to set the Gladiators a modest 146 victory target.
By the close Gloucestershire had reached 19-1 and need 127 further runs on day four to kick their season off with a win.
Resuming day three on 30-0 - still 157 runs away from making the hosts bat again - Smith launched a spirited counter-attack after Derbyshire had slipped to 118-4.
He and Chesney Hughes (60) added 128 for the sixth wicket, however left-armer David Payne (5-76) removed the former and ripped through the Derby tail to put Gloucestershire back on course.
Teenage seamer Liam Norwell enjoyed a debut to remember as he helped Gloucestershire force Derbyshire to follow-on at Bristol.
Norwell contributed 19 to a last-wicket stand of 76 with David Payne, who made an unbeaten 46, before the hosts were eventually bowled out for 343.
However the 19-year-old did his best work with the ball, claiming 6-46 - including the last four wickets for just two runs - as Derbyshire were skittled out for 157 in just 41 overs.
Asked to have another go by home captain Alex Gidman, the visitors reached 30 without loss in the nine overs they faced before the close of play.
Gloucestershire had started the day on 224-6 with Jon Batty unbeaten on 61. He added just nine more runs, though, before falling to Tim Groenewald for his highest score for the county since arriving from Surrey last year.
A defiant 89 from debutant Will Gidman was central to a spirited fightback by Gloucestershire on day one of their LV= County Championship opener against Derbyshire.
Having won the toss the home side were reduced to 65-5 shortly after lunch in Bristol.
But the new-look side, including five Championship debutants, rallied in the afternoon to close the out day on 224-6.
Jonathan Batty, who shared a stand of 156 with Gidman, chipped in with an unbeaten 61, while Tony Palladino (2-23) and Jon Clare (2-46) were the pick of the visiting attack.
Opener Ian Cockbain could only make five on his first appearance for the county before he edged to second slip and Chris Dent fell lbw soon after to make it two for 25.
Greg Smith had Chris Taylor caught behind off a short ball for four and skipper Alex Gidman followed just three runs later, lbw off Palladino.
Richard Coughtrie was bowled by Clare shortly after lunch having faced 84 deliveries for his 17 runs.
But Batty and Gidman knuckled down in determined fashion to steady things for the hosts, until Clare ended their 58-over stand by having the latter caught by Luke Sutton attempting to glance one down the leg side.