Hampshire must again do without an overseas player in their LV County Championship fixture against Lancashire after failing to find a replacement for New Zealand paceman Shane Bond.
The Pakistan Cricket Board scuppered Sohail Tanvir's planned move to the south coast.
The situation is further compounded by Kolpak seam bowler Nantie Hayward, who misses out due to a side strain.
Sutcliffe deputises for Loye
Lancashire are without top-order batsman Mal Loye due to back spasms.
Iain Sutcliffe replaces Loye, who also missed Tuesday's Twenty20 Cup quarter-final defeat to Middlesex with the same problem.
All-rounder Andrew Flintoff continues his quest to prove his fitness following a side strain ahead of a possible return to England colours later in the summer.