With the series is on the line, India will be hoping to bounce back when they host Australia in the third and final T20 international in Hyderabad on Friday, live on Sky Sports Cricket.
Virat Kohli's side took the opening match of the series in a rain-affected contest but Australia roared back on Tuesday to level the series with an eight-wicket victory.
Jason Behrendorff was the star of the show for the Aussies, marking his second T20I with four wickets as David Warner's side recorded a comfortable win to level the three-match series at 1-1.
The left-arm paceman ripped through the hosts' top order in Guwahati before an unbroken third-wicket partnership of 109 from Moises Henriques (62 not out) and Travis Head (48 not out) helped Australia coast to victory.
Australia lost the one-day international series 4-1 but Friday's winner-takes-all clash represents an excellent chance for Warner's side to take a trophy home and end their tour on a high note.
After their impressive performance in Guwahati, Australia are expected to name the same side as they look to carry on the momentum they built at the Rajiv Gandhi International Stadium.
India's spinners Kuldeep Yadav and Yuzvendra Chahal have been key to the success they've enjoyed against Australia in recent weeks, but they weren't as effective in Guwahati on Tuesday, failing to take a wicket and conceding 75 runs from the 45 deliveries they bowled between them.
However, despite the punishment the spinners received Kohli is expected to resist the temptation of making a change, meaning Axar Patel will miss out.
Ashish Nehra, who announced he will retire from cricket during India's T20I series with New Zealand next month, is also expected sit out again.
Watch the third and final T20I between India and Australia from 2.20pm, Friday on Sky Sports Cricket.