Stephen Moore smashed a quickfire 74 to help secure Lancashire a 12-run victory over Derbyshire in the floodlit Friends Life t20 match at Old Trafford.
Moore's half-century helped the hosts post 165-9 off their 20 overs and some tight bowling from spinners Simon Kerrigan and Arron Lilley ensured Derbyshire could manage only 153-6 in reply.
The win was Lancashire's third in six games and it boosts their hopes of qualifying the quarter-finals from the North Group.
Moore plundered five sixes and five fours in his 42-ball knock and was particularly hard on David Wainwright, taking 23 runs off the slow left-armer's third over.
However, that acceleration was desperately needed by a Lancashire side who had initially struggled to dominate the Falcons attack - a modest 38 runs came off the first six overs for the loss of Tom Smith, Karl Brown and Simon Katich, two of the wickets falling to Tim Groenewald who finished with 3-32.
Brief injections of acceleration were supplied by Ashwell Prince (14) and Gareth Cross (21) but Lancashire's final total was probably little more than par on a good pitch.
In contrast to hosts' innings, the Derbyshire reply got off to a fine start with Wes Durston hitting sixes off both Tom Smith and Kabir Ali as 54 runs were plundered off the first six overs.
After Durston departed for 48 the run-rate slowed, but Shivnarine Chanderpaul made an inventive 39 off 31 balls to get his side back into things before being run out by a direct hit from mid-on by Mitchell McClenaghan.
Derbyshire needed 46 runs off the final four overs and skipper Wayne Madsen made 36 in a vain effort to keep up with the asking rate as Kabir Ali and McClenaghan applied the pressure - the New Zealander finishing with 2-26.