Lancashire were on course for their sixth win of the season by the end of rain-affected third day of the LV= County Championship game against Leicestershire at Grace Road.
Having forced the home side to follow on 226 runs behind, Lancashire had them at 128-5 in their second innings at stumps, still trailing by 98 runs.
The biggest threat to top-of-the-table Lancashire's hopes of their fourth win in the last five games looks to be a poor weather forecast for the final day.
Leicestershire began the day on 127-7, still needing 104 runs to save the follow on, and managed only 27 in 9.1 overs.
James Sykes (10) edged behind off Tom Smith who also had Ollie Freckingham (seven) caught in the slip cordon before left-arm spinner Simon Kerrigan brought the innings to a close by trapping Matthew Hoggard lbw without scoring. Smith had figures of 3-35 and Kerrigan 3-52, with Leicestershire all out for 154.
Their second innings could not have started in worse fashion with Greg Smith nailed lbw first ball by a swinging yorker from Kyle Hogg. Fellow opener Michael Thornely soon followed, providing Simon Katich at mid-off with an easy catch off the same bowler.
Ned Eckersley and Shiv Thakor offered some resistance, until a dreadful mix-up saw Eckersley run out for 25 when he was sent back going for a third run and failed to beat Paul Horton's excellent throw from the deep.
That made it 41-3 shortly before lunch, at which point rain began to fall and the players went off. They did not return until four hours later, with 43 overs lost.
But Glen Chapple quickly claimed the fourth wicket on the resumption, with Thakor clipping a catch to square leg having made 14.
A half-century stand between Matt Boyce and Niall O'Brien put the brake on Lancashire's progress for 16 overs until Boyce, on 27, chased a wide delivery from Andrea Agathangelou and edged to wicketkeeper Gareth Cross.
But O'Brien (35 not out) and Tom Wells, unbeaten on 10, saw Leicestershire through to the close and they will now hope that rain may play a major part on the final day.