Durham's hopes of winning the LV= County Championship title were dealt a blow as they lost by 67 runs to reigning champions Nottinghamshire.
Set 321 to win the Division One clash at Trent Bridge and go back above Lancashire in the table, Durham were bowled out for 253. They now sit 10 points back of the Red Rose county, having played a game more.
Graeme White claimed 4-72 to add to his first-innings figures of 3-17, giving the left-arm off-spinner career best match figures. He claimed the last four wickets to seal Notts' fifth triumph of the campaign.
Durham had begun the day on 20-1 but soon suffered an early blow when Michael Di Venuto fell to the fourth ball of the day from Andre Adams.
Nightwatchman Mitchell Claydon also fell quickly but Michael Stoneman and Paul Collingwood (33) shared a stand of 83 to get their side to 118-3 by lunch.
However, Collingwood departed to the fourth ball of the afternoon session, edging Darren Pattinson through to wicketkeeper Chris Read, and Dale Benkenstein then went for a duck, leaving the visitors on 123-5.
When Stoneman's knock of 74 was ended by Luke Fletcher Nottinghamshire were in full control. White did the rest, including taking a diving one-handed return catch to see the back of the dangerous Ian Blackwell (31).
Durham will resume on the third morning at 20-1 in pursuit of a victory target of 321 against Nottinghamshire as wickets continued to tumble at Trent Bridge.
After 13 went down on the opening day, the game continued in fast forward with another 18 falling on day two to leave the home side in a strong position.
Nottinghamshire seamer Andre Adams (3-61) and spinner Graeme White (3-17) each claimed three wickets as Durham, on 44-3 overnight, were bowled out for 195 in their first innings to concede a deficit of 75.
It would have been far more had Dale Benkenstein (49) and Ian Blackwell (52) not shared 91 runs for the fifth wicket, the only stand of any note.
Nottinghamshire lost opening batsman Alex Hales, who scored a century on day one, to the opening ball of their second innings, the first of five wickets for seam bowler Mitchell Claydon (5-54).
Riki Wessels hit 84 but the hosts had slumped to 180-8 before Adams wielded some long handle to finish 53 not out from 48 balls in a total of 245 all out.
Durham, who realistically need a victory to remain in the Division One title hunt, lost Will Smith, lbw to Luke Fletcher for a duck, in the first over of their run chase.
Nottinghamshire opener Alex Hales struck a century as 13 wickets fell on the opening day against title-chasing Durham at Trent Bridge.
England Lions batsman Hales hit 115, including 15 of his 16 fours through the off-side, in a total of 270 all out after the home side had opted to bat first.
He shared half-century stands with Darren Bravo (23) and Riki Wessels (3) for the respective second and third wickets.
But Durham's seamers, led by Mitchell Claydon with 3-84, made regular breakthroughs to dimisss Nottinghamshire in 71.3 overs.
Durham were reduced to 44-3 in reply by the close as Darren Pattinson (2-17) struck twice after Luke Fletcher (1-17) had removed Michael Di Venuto (2) in the third over.