Nottinghamshire's title hopes suffered a blow as they narrowly failed to chase a target of 366 against Durham on the final day at Trent Bridge.
Durham eased their relegation fears with a 16-run success, mainly thanks to the efforts of seamer Mark Wood, making his first County Championship appearance of the season.
Wood, a 22-year-old from Ashington playing in his fourth first-class match, finished with a career-best 5-78 as Nottinghamshire were all out for 349 late in the evening session.
Openers Alex Hales and Riki Wessels launched the run chase with a stand of 168 in 42.1 overs.
Wessels went for 98, caught by Callum Thorp off Chris Rushworth's bowling, but Hales went on to complete his fifth first-class century from 144 balls, including 13 fours.
But Wood accounted for Hales on 101 and Durham chipped away with regular wickets thereafter to ensure the recent resurgence under Paul Collingwood's leadership continued with their third win in a row.
Steven Mullaney was left unbeaten on 60 when Wood trapped last man Andy Carter lbw for a duck to seal the win.
At the start of the day, Durham batted on for four overs to advance their second innings from 301-7 to a declaration at 325-8.
The result, Nottinghamshire's first defeat in the four-day format this season, leaves them in third place in the Division One table, 18 points adrift of leaders Warwickshire who have played a game less. Durham are now 20 points clear of the relegation spots.
Durham are on course for a third straight County Championship victory with Nottinghamshire needing to score more than 340 runs on the final day.
The visitors began Friday on 27 without loss, leading by 67, with Notts needing early wickets to reclaim the momentum.
Mark Stoneman and opening partner Will Smith were watchful and survived the first 45 minutes of play, before Smith edged a defensive shot off seamer Luke Fletcher to Chris Read behind the stumps.
Keaton Jennings fell in the third over after lunch, lbw to Ben Phillips for a patient 31 before opener Mark Stoneman (114) also fell to Phillips, but not before he hit his first century of the season.
With the ball getting softer, Paul Collingwood batted with increasing comfort to extend the lead past 300, despite losing Dale Benkenstein caught at gully off Fletcher and seeing Scott Borthwick bowled through the gate by Graeme White.
But with young all-rounder Mark Wood looking confident, the pair put on 61 for the seventh wicket and survived 14 overs of the new ball before Wood was caught behind off Fletcher for 30, just before the close, leaving Durham well-placed at 301-7.
Graham Onions made the most of his Test omission to record his best figures on day two of Durham's Division One game at Nottinghamshire.
The seamer - sent north from Lord's in the morning - arrived too late to bat in his side's first-innings 194 but then took 9-67 as Notts' reply reached just 154.
By the close Durham took their lead onto 67 without losing either opener, but the day unquestionably belonged to Onions, whose haul was the best in England this summer.
The visitors lost their remaining wickets for 110 after resuming on 85-4, but even as batsman after batsman was being sent back there was comfort in the knowledge Onions was on his way from London.
And the conditions proved just to his liking as the dismissal of Alex Hales - trapped in front - proved the forerunner to a remarkable performance.
All bar two of Onions' victims were out bowled or leg-before, Riki Wessels and Chris Read went to successive balls and only Paul Franks' game half-century prevented total collapse.
In the end Onions' chances of getting all 10 were undone by his own accuracy as he ran out a leaden-footed Luke Fletcher with the score 154-8.
Title-chasing Nottinghamshire were left frustrated by the weather after making a decent start to their Championship game with Durham.
Needing a win to close the gap on Division One leaders Warwickshire, the hosts put Durham in to bat after winning the toss on a green track at Trent Bridge.
However, while two wickets from recalled seamer Luke Fletcher helped reduce the visitors to 85-4 at lunch, persistent rain meant no further play was possible.
Opener Mark Stoneman made 46 for Durham before becoming Fletcher's second victim, and Dale Benkenstein (16 not out) and captain Paul Collingwood (nine no) will resume on day two looking to continue the recent form that has seen the county move away from the relegation zone.
With Fletcher and bowling partner Ben Phillips quick to settle into a good rhythm, Stoneman and former Nottinghamshire batsman Will Smith had both played and missed before the latter lost his off-stump after leaving a good-length ball from Fletcher that came back a fraction.
Jennings was next to go, lbw to Phillips as the left-hander propped forward, and wicketkeeper Phil Mustard was adjudged to have edged a drive against Andy Carter to Read behind the stumps.
All the while Stoneman dug in and quickly seized on any loose deliveries, hitting nine fours, before Fletcher returned for a second spell and found the outside edge for another catch to Read two overs before lunch.