Meek resistance from Pakistan saw Australia open the three-match one-day series between the two with a 93-run win at Sharjah in the United Arab Emirates.
Steve Smith's first ODI hundred had allowed the 'visitors' in the neutral-ground clash in Dubai to post 255-8 from their 50 overs.
It was a total Pakistan got nowhere near in response, with their earlier drop of Smith all the more costly as they were wrapped up for just 162.
They put the all-rounder down on five and he went on to add a further 96 runs, Smith underpinning Australia's entire innings with his knock only really supported by David Warner's 43.
The Baggy Greens could not have got a worse start, losing Aaron Finch just a ball in as he was caught at backward point off Mohammad Irfan.
Smith should have been trailing back after him on five but Sarfraz Ahmed put him down, allowing him to build an 86-run stand with Warner.
That ended when the latter holed out to mid-wicket off Shahid Afridi, but Smith ticked on and added another 47 with George Bailey.
The stand ended with Bailey replicating Warner's dismissal at the hands of Fawad Alam for 18.
Glenn Maxwell posted 21 in Smith's company before hitting Zulfiqar Babar to Afridi at long off, while Afridi (3-46) returned to trap James Faulkner leg before for 11.
Smith's maiden one-day hundred came up in 115 balls, but he was only able to add a run to it before Afridi got him, caught by Wahab Riaz in the deep.
After he went it was a case of how many late runs Australia could accumulate - Brad Haddin made an unbeaten 23 from 27 balls and Mitchell Johnson clubbed 21 from 16, but two wickets from Riaz - Sean Abbott and Johnson - slowed things down.
Ahmed Shehzad gave Pakistan's chase a poor start, nicking Johnson (3-24) to second slip on four, leaving the team nine for one.
Sarfraz steadied the ship a little with a 50-run stand with Asad Shafiq, but was unable to fully atone for his drop, falling to the spin of Nathan Lyon on 34.
The introduction of Lyon really gave Australia a handle on the game, and he snagged Misbah-ul-Haq for a first-ball duck, caught at leg slip.
Asad Shafiq followed for 13 to Johnson, gloved down the legside to Haddin, while Fawad Alam went to the slower bowling of Maxwell for seven.
Afridi made only five before he went to debutant Sean Abbott, caught in the deep and with him went a lot of Pakistan's middle-order power.
Anwar Ali made eight, edging Johnson behind, while Riaz hit Maxwell back to the bowler for five.
Umar Akmal had made steady progress to 46 as the wickets fell, but his 57-ball vigil ended when Kane Richardson cleaned him up between bat and pad.
His exit signalled the end and when Irfan was run out attempting a single, the game was up.