South Africa and Australia will be hoping the rain stays away from Durban so they can finally start their Twenty20 series on Wednesday.
After the opening match was washed out in Port Elizabeth without a ball bowled, both teams will be desperate to see some action to aid their preparations for the upcoming ICC World Twenty20.
The Proteas are yet to play in the shortest format of the game in 2014, leaving them little time to view combinations ahead of travelling to Bangladesh.
They have, though, won six of their last eight fixtures, and one of their two defeats came when they had already secured the series against Sri Lanka.
Dale Steyn will wait to play until the third and final match at Centurion on Friday, but Albie Morkel could make his first appearance for South Africa since the last Twenty20 tournament in Sri Lanka two years ago.
Beuran Hendricks also looks set to be rewarded for his excellent form in domestic action with a debut for his country in a side that will be led by batsman Faf du Plessis.
Australia, meanwhile, will be back in action in 20-over cricket for the first time since whitewashing England 3-0 on home soil at the start of the year.
The tourists look certain to take no risks with Brad Hogg, a minor hamstring injury meaning the 43-year-old spinner is unlikely to appear at Kingsmead.
"It's a weird one. I can do everything except bowl," Hogg told Cricket Australia's website.
"Every time I plant that front leg down, I can't get over there. But I'm glad it's happened now and not over in Bangladesh.
"If it was a big game - you'd take the medications and definitely would (play). But I think we're taking a conservative approach at the moment so I'm right for the World Cup."
James Faulkner is also ruled out with a knee problem, though it is hoped he will be fit to feature against Pakistan in Australia's opening World T20 fixture, which takes place on March 23.
Cameron White excelled against England on home soil but with David Warner's return, it seems he's in a battle for a berth in the middle order along with Brad Hodge. That is, of course, provided the rain does stay away this time.
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