England start life without Kevin Pietersen in Antigua on Friday when they take on West Indies in the first match of their limited-overs tour.
A youthful England squad - comprising only players who will be involved in the upcoming World Twenty20 in Bangladesh - will take on West Indies in three ODIs and three T20Is, seeking some much-needed form after a disastrous winter in Australia.
Pietersen's international axing has dominated the pre-series build-up and captain Stuart Broad and coach Ashley Giles have now been tasked with starting the England rebuilding process, beginning at the Sir Vivian Richards Stadium.
Their opponents, West Indies, come into the series without star duo Chris Gayle and Kieron Pollard due to injury, while pace bowler Kemar Roach is a noticeable absentee from their bowling attack.
England gave a clue as to what starting XI they will field in the opening ODI against the University of the West Indies Vice-Chancellor's XI on Tuesday, where Joe Root scored a timely century in a 29-run win.
Luke Wright and Alex Hales look set to open the batting in the absence of rested pair Alastair Cook and Ian Bell with Ben Stokes, who made 58 in the recent warm-up fixture, lining up at No 3.
Eoin Morgan's place in the batting order has been hotly-debated but Root flourished at No 4 this week and should retain that place above the Irishman, who will have a major say in England's upcoming limited-overs fortunes.
Jos Buttler batted above Ravi Bopara at No 6 against the West Indies Vice-Chancellor's XI and on their day are two of the best finishers in world cricket.
Tim Bresnan could flourish on the Caribbean wickets and is expected to share pace bowling duties with captain Broad and Barbados-born Chris Jordan. James Tredwell offers the premier spin option.
The absence of Gayle at the top of the hosts' batting line-up is a serious blow to their chances of building some much-needed momentum ahead of their World T20 title defence next month.
Gayle suffered a lower back injury in the first of two T20's against Ireland the previous week in his native Jamaica and has been replaced at the top of the order by experienced right-hander Dwayne Smith.
Marlon Samuels enjoyed plenty of success the last time the sides met in England and will shoulder a lot of the batting responsibilities with Darren and Dwayne Bravo's runs also key to the cause.
There is plenty of excitement in the Caribbean over the potential of 6ft 7in paceman Jason Holder, who is expected to open the bowling alongside Ravi Rampaul in the absence of Roach.
All three one-dayers will take place at the Sir Vivian Richards Stadium on February 28, March 2 and March 5.
West Indies (probable): Dwayne Bravo (capt), Dwayne Smith, Lendl Simmons, Darren Bravo, Marlon Samuels, Denesh Ramdin, Darren Sammy, Nikita Miller, Sunil Narine, Jason Holder, Ravi Rampaul.
England (probable): Stuart Broad (capt), Luke Wright, Alex Hales, Ben Stokes, Joe Root, Eoin Morgan, Jos Buttler, Ravi Bopara, Tim Bresnan, Chris Jordan, James Tredwell.
Watch the first one-day international between West Indies and England live on Sky Sports 2HD from 1pm on Friday.
Nick Knight has been telling Sky Sports News Radio that England have to move on from the Kevin Pietersen era and Eoin Morgan is the perfect man to replace him as match winner.
Hear the full ODI series preview here:
What will be the outcome of West Indies v England in the ODIs be?
3-0 West Indies
2-1 West Indies