Durham completed a 146-run victory over a stubborn Yorkshire outfit on the final day at Headingley on Sunday.
Resuming on 88-2 and still 401 runs behind, Yorkshire lost early wickets with Joe Root failing to add to his overnight 38 when he was caught behind off Graham Onions.
Skipper Andrew Gale was dismissed six runs later and Gerard Brophy was lbw for 20, before Adil Rashid fell to Liam Plunkett for the fourth wicket of the morning session to make it 158-6.
Jonathan Bairstow and Richard Pyrah steadied things with a 16-over stand of 67, but the former fell to a smart slip catch by Michael Di Venuto off leg-spinner Scott Borthwick for 81.
Pyrah and Ryan Sidebottom added 98 for the eighth-wicket until Sidebottom edged Plunkett to Richardson on 31.
Steve Patterson was lbw to his first delivery and Moin Ashraf battled bravely until Pyrah was pinned lbw by Borthwick to end the match at 5.15pm.
He had batted for 211 minutes, faced 184 balls and hit 12 boundaries for a fine 87, but it was not enough to prevent the visitors claiming their first win of the season.
A fine knock of 150 by acting captain Dale Benkenstein has put Durham in a strong position to push for victory on the final day against Yorkshire.
The hosts reached the close on 83-2 at Headingley from 32 overs after being set a monumental target of 490 in four full sessions.
Young opener Joe Root will resume again on 38 not out having shared a 64-run stand for the first wicket with Adam Lyth (26). Anthony McGrath was the other batsman to be dismissed, falling to Ian Blackwell for just seven.
The Tykes still have a lot of work to do if they are to escape unscathed, though, after Benkenstein, filling in as skipper due to an injury to Phil Mustard, had registered his third ton against the county in four-day cricket.
The veteran batsman shared a record sixth-wicket stand of 187 with Michael Richardson, who followed up his 67 in the first innings with an unbeaten 73.
The duo had come together with Durham in a spot of bother at 124-5 but proceeded to bat their opponents out of the game. Benkenstein's departure on the stroke of tea led to a declaration at 311-6.
Graham Onions celebrated his return to first-class cricket with a five-wicket haul as Yorkshire collapsed to 149 all out on day two at Headingley.
Onions, who had been out of action since January last year, ended with figures of 5-51 and Callum Thorp chipped in with 3-33, as Yorkshire ended their first innings trailing by 178 runs.
But the visitors declined to enforce the follow-on after tea and were 64-3 in their second innings, giving them an overall lead of 242, when bad light ended play.
Resuming on 326-9, Durham added only a single before Onions holed out off Ryan Sidebottom, though he soon made an impact with the ball.
Adam Lyth pulled his second ball straight into the hands of Ben Stokes at square leg and after a brief fightback, Yorkshire's last eight men fell for just 49 runs, to leave Gerard Brophy stranded following a stubborn 75-ball 19.
Durham lost both openers in consecutive overs at the start of their second innings, Michael Di Venuto edging Sidebottom to first slip and Will Smith falling lbw to Moin Ashraf, while Stokes then played on in worsening light.
Durham battled back on day one after a middle-order collapse against Yorkshire to reach the close at Headingley on 326-9.
The visitors had at one stage been 106 without loss but slipped to 123-5 and then 196-8, Ryan Sidebottom and Richard Pyrah each taking three wickets.
However Durham's lower order offered stubborn resistance, debutant wicketkeeper Michael Richardson (67), Liam Plunkett (65 not out) and Callum Thorp (41) all making decent contributions.
Having chosen to bat first after winning the toss, the visitors were given a superb start thanks to Michael Di Venuto's 74 from just 84 balls.
Pyrah put the brakes on with two wickets in the space of three balls and when Sidebottom - now back with his first county - ripped out the middle order, Yorkshire looked set to bowl their opponents out cheaply.
Those hopes disappeared, though, as Durham fought hard; Richardson - the son of ICC general manager and former South Africa wicketkeeper, Dave Richardson - started the fightback having only been a late call-up, before Plunkett and Thorp shared a 103-run stand for the ninth wicket.