Martin Johnson has brought Joe Worsley and Mike Tindall into England's starting XV to play Wales on Saturday.
Gloucester No.8 Luke Narraway believes a loss against Cardiff will end their hopes of a place in the Heineken Cup quarter-finals.
Gloucester maintained their pursuit of Cardiff Blues in Pool Six with a bonus-point victory over Calvisano.
Gloucester number eight Luke Narraway has signed a two-year contract extension keeping him at Kingsholm until 2010.
Paul Hodgson, Luke Narraway and Michael Lipman are to stay with England's training squad in the build-up to the Six Nations opener.
England and London Wasps are anxiously waiting news on the full extent of Paul Sackey's illness.

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