Davinson Sanchez and Kasper Dolberg both scored twice as Ajax beat Zwolle 5-1 while PSV won at Excelsior.
Eric Botteghin struck a late winner as Feyenoord maintained their perfect start to the Eredivisie season with a 1-0 win at PSV.
Luuk de Jong capped a 24-minute blitz as PSV stormed back to the top of the Eredivisie with a 4-1 win over NEC in Nijmegen.
Dirk Kuyt scored twice as Feyenoord came from behind against Excelsior to maintain their 100 per cent Eredivisie record.
Defending champions PSV Eindhoven defeated PEC Zwolle 4-0 to secure top spot in the Eredivisie.
Ajax were held to a draw by Roda JC in a four-goal thriller on Saturday, while Vitesse lost at home to ADO Den Haag.