Sale Sharks boss Steve Diamond has described Leicester as "the Manchester United of Aviva Premiership rugby" prior to Saturday's meeting between the clubs.
Dai Young is expecting big things from Marty Moore at Wasps and says it would be a surprise if the prop is not recalled by Ireland.
Danny Care misses Harlequins' trip to Wasps while David Wilson is on the bench for Newcastle's clash with Worcester.
Mike Phillips starts for Sale against Leicester while Billy Twelvetrees will make his 100th start for Gloucester.
Laurie Fisher has urged Gloucester to "treasure the ball" in Saturday's Aviva Premiership west country derby against Bath at Kingsholm.
England internationals Jack Nowell and George Kruis return to action this weekend as the Premiership kicks off on Friday.
Sale half-back Peter Stringer could miss three months of the Aviva Premiership campaign after tearing his biceps tendon.
Bath have agreed a deal to sign centre Robbie Fruean from Hawke's Bay as well as bringing in Dragons prop Shaun Knight on loan.
Three Ireland internationals are joined by six Premiership players while two Top 14 hat-trick heroes battle it out for a place on the wing.
Stuart Barnes on Harlequins beating Saracens, Johnny Sexton's bright start to the season and positives for Italian rugby.
Owen Williams kicked 17 points as Leicester ended Bath's 100 per cent record with a 34-14 Aviva Premiership victory.
Sale came back from trailing 31-17 to gain a late draw against Worcester in a nine-try thriller at Sixways.
Dai Young eased fears over Danny Cipriani after the fly-half left the field with a head injury in Wasps' victory over Saints.
Saracens slumped to their first defeat in six months as Harlequins stunned the double winners 17-10 at the Stoop.
Wasps maintained their unbeaten start to the Aviva Premiership season with a 20-15 victory against a sloppy Northampton.
Exeter underlined the huge task facing Bristol to secure top-flight survival this season as they ran out 41-17 winners at Ashton Gate.
Newcastle secured a second Premiership win of the season as they surprised Gloucester with an 18-13 win at Kingsholm.
The RFU used photographic evidence as part of its decision to ban Chris Ashton for 13 weeks, the disciplinary panel's written judgement has revealed.
Bath hope a small group of residents will not block their attempts to build a new stadium on the existing Recreation Ground site.
Saracens winger Chris Ashton has been banned for 13 weeks after being found guilty of biting Northampton's Alex Waller.