Friday 23 October 2015 11:05, UK
England trio Owen Farrell, Jonny May and Ben Morgan return to club duty on Friday night as Saracens visit Gloucester, while Worcester travel to Sale.
Gloucester v Saracens (7.45pm)
Gloucester have given starts to wings David Halaifonua and May, fly-half James Hook and No 8 Morgan following their return from World Cup duty.
Charlie Sharples, who scored a try in the Cherry and Whites' opening round win at Newcastle, switches from the wing to full-back while captain Billy Twelvetrees moves to outside centre.
Saracens rest lock Maro Itoje so hooker Jamie George captains a team that includes returning England internationals George Kruis and Farrell.
Gloucester: 15 Charlie Sharples, 14 David Halaifonua, 13 Billy Twelvetrees (c), 12 Bill Meakes, 11 Jonny May, 10 James Hook, 9 Willi Heinz; 1 Paddy McAllister, 2 Richard Hibbard, 3 John Afoa, 4 Tom Savage, 5 Sione Kalamafoni, 6 Lewis Ludlow, 7 Matt Kvesic, 8 Ben Morgan.
Replacements: 16 Tom Lindsay, 17 Yann Thomas, 18 Paul Doran-Jones, 19 Elliott Stooke, 20 Jacob Rowan, 21 Callum Braley, 22 Steve McColl, 23 Mark Atkinson.
Saracens: 15 Alex Goode, 14 Chris Ashton, 13 Tim Streather, 12 Owen Farrell, 11 Mike Ellery, 10 Charlie Hodgson, 9 Neil De Kock; 1 Mako Vunipola, 2 Jamie George (c), 3 Petrus Du Plessis, 4 George Kruis, 5 Jim Hamilton, 6 Michael Rhodes, 7 Kelly Brown, 8 Jackson Wray.
Replacements: 16 Jared Saunders, 17 Rhys Gill, 18 Titi Lamositele, 19 Alistair Hargreaves, 20 Will Fraser, 21 Richard Wigglesworth, 22 Nick Tompkins, 23 Ben Ransom.
Sale Sharks v Worcester Warriors (8pm)
Samoa centre Johnny Leota starts following his return from World Cup duty as Sale welcome Northampton-conquering Worcester to the AJ Bell Stadium.
Josh Beaumont is given the nod at No 8 and prop Vadim Cobilas makes his 100th appearance for the Sharks, who suffered a 41-3 hiding at Saracens in round one.
Worcester have named an unchanged starting XV following their last-gasp victory over Saints, with drop goal hero Tom Heathcote retained at fly-half.
Sale: 15 Mike Haley, 14 Tom Arscott, 13 Johnny Leota, 12 Sam Tuitupou, 11 Will Addison, 10 Danny Cipriani, 9 Chris Cusiter; 1 Ross Harrison, 2 Tommy Taylor, 3 Vadim Cobilas, 4 Bryn Evans, 5 Jonathan Mills, 6 Dan Braid (c), 7 David Seymour, 8 Josh Beaumont.
Replacements: 16 Neil Briggs, 17 James Flynn, 18 Brian Mujati, 19 Andrei Ostrikov, 20 TJ Ioane, 21 Peter Stringer, 22 Nick Macleod, 23 Sam James.
Worcester: 15 Chris Pennell, 14 Tom Biggs, 13 Wynand Olivier, 12 Ryan Mills, 11 Cooper Vuna, 10 Tom Heathcote, 9 Jonny Arr; 1 Na'ama Leleimalefaga, 2 Niall Annett, 3 Nick Schonert, 4 Donncha O'Callaghan, 5 Darren Barry, 6 Phil Dowson, 7 Marco Mama, 8 GJ van Velze (c).
Replacements: 16 Dan George, 17 Val Rapava Ruskin, 18 Joe Rees, 19 Tevita Cavubati, 20 Matt Cox, 21 Charlie Mulchrone, 22 Ryan Lamb, 23 Ben Howard.