Leicester will aim to maintain their Aviva Premiership play-off push on Friday - but they face a considerable task against Harlequins.
Harlequins have signed prop Phil Swainston from their Aviva Premiership rivals Wasps.
Bath's Francois Louw and Kahn Fotuali'i have been banned for two weeks.
Bath continued their Premiership play-off push after centre Max Clark's try edged a 22-12 win over Harlequins.
Tom Varndell broke the Premiership try-scoring record but it was in vain as Bristol were crushed 42-8 by Harlequins.
Harlequins have agreed a deal to sign scrum-half Dave Lewis from Exeter Chiefs for next season.
Northampton stayed in Anglo-Welsh contention with a 50-10 crushing of Scarlets while Harlequins lost 13-10 at home to Sale.
Harlequins came from behind to put themselves top of the Anglo-Welsh Cup Pool 3 with a 28-22 victory over Worcester.
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