Danny Cipriani missed a last-minute penalty as Sale Sharks had to settle for a 15-15 draw against Newcastle Falcons.
Sale director of rugby Steve Diamond was frustrated by his team's display as they were held to a draw by Newcastle.
All the team news for Saturday's Aviva Premiership fixtures, including the double header at Twickenham.
A Mark Wilson hat-trick and four tries from Marcus Watson eased Newcastle to a 55-7 victory against Enisei-STM.
Newcastle got their Challenge Cup off to a poor start with a 13-9 away defeat to Brive on Friday night.
Scotland flanker John Hardie makes his Edinburgh debut in Friday's Challenge Cup opener against Grenoble at Murrayfield.
Promoted Worcester kept up their impressive start to the season with a bonus-point 28-20 win over Newcastle at Sixways.
Exeter banished the memories of last season's loss at Kingston Park with a comprehensive 41-3 victory over Newcastle.
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