All the team news ahead of Thursday's European Challenge Cup fixture between Grenoble and the Ospreys.
Wales flanker Dan Lydiate will not play again this season after suffering a knee injury, his club Ospreys have announced.
Ospreys moved up to second in the Guinness Pro12 table with a solid 31-22 bonus-point victory over Edinburgh.
Wales international James Hook will return "home" to Ospreys next season after six years away.
Ospreys have secured the future of former world junior player of the year Sam Davies on a new long-term contract.
Ospreys ran in four tries to earn a 22-5 bonus-point success at 14-man Glasgow and move closer to the top of the Guinness PRO12 table.
Newport Gwent Dragons secured bragging rights with a 36-21 win over the Scarlets in the Anglo-Welsh Cup.
Teenager Keelan Giles could be in line for a Test debut when Wales face Japan next Saturday.
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