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Four-time Grand Final winners St Helens kick-off the new 2013 Super League season against the Huddersfield Giants at Langtree Park.
Saints' new head coach Nathan Brown has a near fully-fit squad to choose from with only Paul Clough unavailable to face the Giants through injury.
Brown's first game at the helm of Saints is against former club Huddersfield, with whom the Australian spent three years in charge.
"If you have got a big side that plays a certain style of footy you need those big guys to play," he said. "Huddersfield are going to be pretty formidable through that middle part of the field.
"It is the start of the year, first game at home and we want to get it off to a positive start. Huddersfield will want to get off to a good start themselves."
Huddersfield will hand debuts to Stuart Fielden and Craig Kopczak for Saturday's clash.
Fielden joined from Wigan on a two-year contract during the close season while Wales international Kopczak played for the Bradford Bulls in 2012.
Brown's replacement at Huddersfield is Paul Anderson and the former Great Britain international knows the importance of making a positive start to the season.
"This is such an important week that we can't afford to let anything distract us in what we're striving to achieve," Anderson told the Huddersfield Daily Examiner.
"It's been such a long and exhausting pre-season that we don't want all that to come to waste on our opening night."
St Helens: Wellens, Gardner, Turner, Soliola, Meli, Hohaia, Lomax, Perry, Roby, McCarthy-Scarsbrook, Puletua, Wilkin, Manu, Laffranchi, Flanagan, Jones, Gaskell, Makinson, Greenwood
Huddersfield Giants : Grix, George, Cudjoe, Wardle, McGillvary, Brough, Robinson, Crabtree, Lunt, Kopczak, Ferres, O'Donnell, Faiumu, Patrick, Chan, Murphy, Cording, Ferguson, Fielden
|Click here for more betting|
|9||Hull K R||15||14|
|14||Salford City Reds||15||7|
|Saturday 25th May|
|12:00||Catalan Dragons vs London Broncos|
|14:15||Castleford vs Wakefield|
|16:30||Hull vs Hull K R|
|18:45||St Helens vs Warrington|
|Sunday 26th May|
|15:00||Salford vs Widnes|
|17:15||Bradford vs Huddersfield|
|19:30||Leeds vs Wigan|
|Friday 31st May|
|20:00||Hull vs Leeds|
|Saturday 1st June|
|15:00||London Broncos vs Castleford|
|Sunday 2nd June|
|15:00||Hull K R vs Bradford|
|Monday 20th May|
|Leeds 22 - 30 St Helens|
|Sunday 19th May|
|Hull K R 44 - 18 Wakefield|
|Saturday 18th May|
|London Broncos 6 - 64 Wigan|
|Catalan Dragons 39 - 30 Castleford|
|Friday 17th May|
|Widnes 22 - 36 Huddersfield|
|Salford 7 - 28 Bradford|
|Warrington 16 - 26 Hull|
|Sunday 5th May|
|Castleford 32 - 24 Hull K R|
|Huddersfield 12 - 34 Warrington|
|Saturday 4th May|
|Wakefield 30 - 12 Catalan Dragons|
Read the thoughts and opinions of Stevo with skysports.com