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Four-time Grand Final winners St Helens kick-off the new 2013 Super League season against the Huddersfield Giants at Langtree Park.
Saints' new head coach Nathan Brown has a near fully-fit squad to choose from with only Paul Clough unavailable to face the Giants through injury.
Brown's first game at the helm of Saints is against former club Huddersfield, with whom the Australian spent three years in charge.
"If you have got a big side that plays a certain style of footy you need those big guys to play," he said. "Huddersfield are going to be pretty formidable through that middle part of the field.
"It is the start of the year, first game at home and we want to get it off to a positive start. Huddersfield will want to get off to a good start themselves."
Huddersfield will hand debuts to Stuart Fielden and Craig Kopczak for Saturday's clash.
Fielden joined from Wigan on a two-year contract during the close season while Wales international Kopczak played for the Bradford Bulls in 2012.
Brown's replacement at Huddersfield is Paul Anderson and the former Great Britain international knows the importance of making a positive start to the season.
"This is such an important week that we can't afford to let anything distract us in what we're striving to achieve," Anderson told the Huddersfield Daily Examiner.
"It's been such a long and exhausting pre-season that we don't want all that to come to waste on our opening night."
St Helens: Wellens, Gardner, Turner, Soliola, Meli, Hohaia, Lomax, Perry, Roby, McCarthy-Scarsbrook, Puletua, Wilkin, Manu, Laffranchi, Flanagan, Jones, Gaskell, Makinson, Greenwood
Huddersfield Giants : Grix, George, Cudjoe, Wardle, McGillvary, Brough, Robinson, Crabtree, Lunt, Kopczak, Ferres, O'Donnell, Faiumu, Patrick, Chan, Murphy, Cording, Ferguson, Fielden
|Click here for more betting|
|7||Hull K R||9||9|
|10||Salford Red Devils||9||8|
|14||Bradford Bulls *||9||-2|
|Monday 21st April|
|15:00||Wigan vs Bradford|
|15:00||Widnes vs St Helens|
|15:00||Huddersfield vs Wakefield|
|15:00||Hull vs London Broncos|
|15:00||Leeds vs Salford|
|15:30||Castleford vs Warrington|
|17:00||Catalan Dragons vs Hull K R|
|Thursday 1st May|
|20:00||St Helens vs London Broncos|
|Friday 2nd May|
|20:00||Leeds vs Wigan|
|Saturday 3rd May|
|18:00||Catalan Dragons vs Salford|
|Friday 18th April|
|Salford 22 - 42 Huddersfield|
|Wakefield 20 - 43 Castleford|
|Warrington 44 - 6 Widnes|
|St Helens 14 - 33 Wigan|
|Thursday 17th April|
|Hull K R 21 - 20 Hull|
|Bradford 6 - 46 Leeds|
|London Broncos 22 - 28 Catalan Dragons|
|Saturday 12th April|
|Catalan Dragons 42 - 20 Widnes|
|Friday 11th April|
|Warrington 12 - 25 Hull K R|
|Wigan 36 - 14 London Broncos|
Read the thoughts and opinions of Stevo with skysports.com