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Wigan have included full-back Sam Tomkins in their 19-man squad for Sunday's visit of London after he missed last week's defeat at Huddersfield with a shoulder problem.
Second rower Chris Tuson makes his first appearance of the season for the Warriors after recovering from a quad injury. Centre Darrell Goulding is ill and winger Anthony Gelling injured.
Veteran hooker Ben Fisher is set to make his debut for London. Fisher, who turned 32 earlier this month, joined the Broncos as assistant coach at the end of last season but the club took the precaution of lodging his playing registration with the Rugby Football League.
"It was always part of our plans, it was an option from day one," said London head coach Tony Rea. "He's looked sharp in training this week."
Fisher, an Australian-born Scotland international, made 124 Super League appearances for Hull KR from 2007-11 and made 14 appearances for Catalan Dragons last year.
Utility back Dan Sarginson is in line for his first appearance of the season after gaining match fitness with Hemel Stags.
Full-back Luke Dorn returns in place of Michael Robertson while Alex Hurst and Jamie O'Callaghan also miss out.
The Broncos are one of only two clubs yet to win a match after the first three rounds of Super League.
Wigan squad: Burke, Charnley, Crosby, Dudson, Farrell, Flower, Green, Hughes, McIlorum, Mossop, O'Loughlin, Powell, Richards, Smith, Taylor, Thornley, L Tomkins, S Tomkins, Tuson
London squad: Bailey, Bryant, Channing, Cook, Colbon, Dixon, Dorn, Fisher, Gower, Kaufusi, Krasniqi, Lee, Melling, Randall, Rodney, Sarginson, Wheeldon, Witt, Lovell
|Click here for more betting|
|8||Salford Red Devils||4||4|
|11||Hull K R||4||1|
|14||Bradford Bulls *||4||-2|
|Friday 14th March|
|20:00||Leeds vs Widnes|
|20:00||St Helens vs Catalan Dragons|
|20:00||Wigan vs Hull K R|
|20:00||Salford vs Warrington|
|Saturday 15th March|
|15:00||London Broncos vs Wakefield|
|Sunday 16th March|
|15:00||Bradford vs Huddersfield|
|15:30||Castleford vs Hull|
|Thursday 20th March|
|20:00||Warrington vs Wigan|
|Friday 21st March|
|20:00||Leeds vs London Broncos|
|Saturday 22nd March|
|17:30||Catalan Dragons vs Huddersfield|
|Sunday 9th March|
|Castleford 36 - 31 Wigan|
|London Broncos 16 - 44 Warrington|
|Wakefield 56 - 14 Catalan Dragons|
|Friday 7th March|
|Hull 44 - 16 Bradford|
|Huddersfield 12 - 12 Leeds|
|St Helens 38 - 18 Hull K R|
|Thursday 6th March|
|Widnes 32 - 18 Salford|
|Sunday 2nd March|
|Warrington 18 - 16 Hull|
|Bradford 25 - 12 London Broncos|
|Wigan 46 - 24 Wakefield|
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