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Connacht welcome back Denis Buckley to their front row for the RaboDirect PRO12 clash with bottom club Aironi.
Buckley replaces the injured Brett Wilkinson in the only change to the side that beat Ulster last time out.
"We're looking for a strong performance and to finish the season on a high," said head coach Eric Elwood.
"We've had some excellent results in recent weeks and we hope to build on that and finish on an up. It'll be a big day for the likes of Ray (Ofisa) and Henry (Fa'afili) playing in front of the home crowd for the last time so it would be great to give them the send-off they deserve and finish with a win."
Aironi head to Galway for their last-ever away match in the competition with just one change to their starting XV
Giovanbattista Venditti returns on the wing, with Sinoti Sinoti moving to outside centre in place of the benched Gilberto Pavan.
Also among the replacements, Paolo Buso returns from a long injury break.
Connacht: 15 Gavin Duffy (c), 14 Tiernan O'Halloran, 13 Kyle Tonetti, 12 Henry Fa'afili, 11 Fetu'u Vainikolo, 10 Miah Nikora, 9 Frank Murphy, 8 George Naoupu, 7 Ray Ofisa, 6 John Muldoon, 5 Mike McCarthy, 4 Michael Swift, 3 Ronan Loughney, 2 Ethienne Reynecke, 1 Denis Buckley.
Replacements: 16 Adrian Flavin, 17 Stewart Maguire, 18 Rodney Ah You, 19 Mick Kearney, 20 Johnny O'Connor, 21 Paul O'Donohoe,. 22 Matthew Jarvis, 23 Eoin Griffin.
Aironi: 15 Tito Tebaldi, 14 Giulio Toniolatti, 13 Sinoti Sinoti, 12 Matteo Pratichetti, 11 Giovanbattista Venditti, 10 Luciano Orquera, 9 Tyson Keats, 8 Josh Sole, 7 Simone Favaro, 6 Nicola Cattina; 5 Marco Bortolami (cap), 4 Quintin Geldenhuys; 3 Lorenzo Romano, 2 Fabio Ongaro, 1 Matias Aguero.
Replacements: 16 Tommaso D'Apice, 17 Alberto De Marchi, 18 Luca Redolfini, 19 Joshua Furno, 20 Nick Williams, 21 Naas Olivier, 22 Gilberto Pavan, 23 Paolo Buso.
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|Friday 18th April|
|17:00||Leinster vs Benetton Treviso|
|19:35||Glasgow vs Ulster|
|Saturday 19th April|
|14:30||Zebre vs Edinburgh|
|18:15||Connacht vs Munster|
|Sunday 20th April|
|14:00||Cardiff Blues vs Scarlets|
|16:45||Newport Gwent D'gons vs Ospreys|
|Saturday 26th April|
|19:05||Glasgow vs Edinburgh|
|Thursday 1st May|
|17:00||Zebre vs Ospreys|
|Friday 2nd May|
|19:00||Benetton Treviso vs Glasgow|
|19:05||Scarlets vs Newport Gwent D'gons|
|19:30||Ulster vs Leinster|
|Saturday 3rd May|
|17:00||Edinburgh vs Munster|
|17:00||Connacht vs Cardiff Blues|
|Saturday 10th May|
|18:30||Leinster vs Edinburgh|
|18:30||Ospreys vs Connacht|
|18:30||Newport Gwent D'gons vs Benetton Treviso|
|18:30||Munster vs Ulster|
|18:30||Scarlets vs Cardiff Blues|
|18:30||Glasgow vs Zebre|
|Saturday 12th April|
|Munster 5 - 22 Glasgow|
|Scarlets 27 - 20 Zebre|
|Benetton Treviso 45 - 27 Newport Gwent D'gons|
|Friday 11th April|
|Edinburgh 22 - 29 Cardiff Blues|
|Ulster 58 - 12 Connacht|
|Ospreys 25 - 19 Leinster|
|Friday 4th April|
|Glasgow 29 - 10 Benetton Treviso|
|Thursday 3rd April|
|Newport Gwent D'gons 19 - 23 Edinburgh|
|Sunday 30th March|
|Scarlets 32 - 30 Connacht|
|Saturday 29th March|
|Leinster 22 - 18 Munster|
|Cardiff Blues 28 - 23 Ulster|
|Benetton Treviso 20 - 16 Edinburgh|
|Zebre 25 - 25 Newport Gwent D'gons|
|Friday 28th March|
|Glasgow 11 - 9 Ospreys|
|Sunday 23rd March|
|Newport Gwent D'gons 8 - 24 Connacht|
|Saturday 22nd March|
|Munster 14 - 3 Benetton Treviso|
|Glasgow 14 - 6 Scarlets|
|Friday 21st March|
|Edinburgh 3 - 9 Ulster|
|Leinster 27 - 0 Zebre|
|Ospreys 34 - 9 Cardiff Blues|
|Friday 14th March|
|Ulster 26 - 13 Scarlets|
|Saturday 1st March|
|Leinster 28 - 25 Glasgow|
|Scarlets 18 - 13 Munster|
|Connacht 38 - 6 Benetton Treviso|
|Zebre 15 - 10 Cardiff Blues|
Read the thoughts and opinions of Stuart Barnes with skysports.com