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Scarlets will be confident of boosting their play-off hopes when they take on rock-bottom Aironi in RaboDirect PRO12 action.
The Welsh team, who are five points behind Munster and Glasgow Warriors, require a bonus-point win to cut the gap to the play-off spots.
Aironi are targeting a fifth win this season, and the first one against a Welsh club, after previously beating Edinburgh, Treviso, Connacht and Munster.
Full-back Tito Tebaldi makes his 20th appearance for the Italians while wings Giulio Toniolatti and Sinoti Sinoti and centres Gilberto Pavan and Matteo Pratichetti complete the three-quarter line.
In the half-backs, Luciano Orquera (who needs one more points to reach 100 points scored in all competitions this season) pairs up with scrum-half Tyson Keats.
Up front, Josh Sole is back at number eight to partner Simone Favaro and Nicola Cattina in the back row.
In the second row Aironi can count on Quintin Geldenhuys and captain Marco Bortolami, whilst the front three comprises experienced prop Matias Aguero, hooker Fabio Ongaro and young tighthead prop Lorenzo Romano.
Wales centre Jon Davies will captain the Scarlets for the first time. Dom Day comes back into the second row with Aaron Shingler who returns from a toe injury and, in an unchanged back row, Josh Turnbull is named as vice-captain.
Young Wales and Scarlets Prop Rhodri Jones moves from loosehead prop last weekend to give him an opportunity at tighthead, furthering his development and experience as a key front row player for the future.
"We know this is a must-win game for us out in Italy and the boys have been frustrated after their performance in Brive last weekend in the quarter-final," said Scarlets coach Nigel Davies.
"This is a time or them to get some momentum back and we know we are still in with a fighting chance with our league campaign."
Aironi: 15 Tito Tebaldi; 14 Giulio Toniolatti, 13 Gilberto Pavan, 12 Matteo Pratichetti, 11 Sinoti Sinoti; 10 Luciano Orquera, 9 Tyson Keats; 8 Josh Sole, 7 Simone Favaro, 6 Nicola Cattina; 5 Marco Bortolami (cap), 4 Quintin Geldenhuys; 3 Lorenzo Romano, 2 Fabio Ongaro, 1 Matias Aguero. Replacements: 16 Tommaso D'Apice, 17 Alberto De Marchi, 18 Salvatore Perugini, 19 Joshua Furno, 20 Nick Williams, 21 Filippo Ferrarini, 22 Naas Olivier, 23 Giovanbattista Venditti.
Scarlets: 15 Liam Williams, 14 Sean Lamont, 13 Nick Reynolds, 12 Jon Davies (c), 11 Andy Fenby, 10 Rhys Priestland, 9 Gareth Davies, 8 Ben Morgan, 7 Johnathan Edwards, 6 Josh Turnbull, 5 Dominic Day, 4 Aaron Shingler, 3 Rhodri Jones,2 Ken Owens, 1 Phil John.
Replacements: Matthew Rees, Peter Edwards, Simon Gardiner, Mat Gilbert, Kieran Murphy, Stephen Jones, Viliame Iongi.
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|Saturday 26th April|
|19:05||Glasgow vs Edinburgh|
|Thursday 1st May|
|17:00||Zebre vs Ospreys|
|Friday 2nd May|
|19:00||Benetton Treviso vs Glasgow|
|19:05||Scarlets vs Newport Gwent D'gons|
|19:30||Ulster vs Leinster|
|Saturday 3rd May|
|17:00||Edinburgh vs Munster|
|17:00||Connacht vs Cardiff Blues|
|Saturday 10th May|
|18:30||Leinster vs Edinburgh|
|18:30||Scarlets vs Cardiff Blues|
|18:30||Ospreys vs Connacht|
|18:30||Newport Gwent D'gons vs Benetton Treviso|
|18:30||Munster vs Ulster|
|18:30||Glasgow vs Zebre|
|Sunday 20th April|
|Newport Gwent D'gons 10 - 20 Ospreys|
|Cardiff Blues 17 - 13 Scarlets|
|Saturday 19th April|
|Connacht 23 - 32 Munster|
|Zebre 26 - 13 Edinburgh|
|Friday 18th April|
|Glasgow 27 - 9 Ulster|
|Leinster 62 - 7 Benetton Treviso|
|Saturday 12th April|
|Munster 5 - 22 Glasgow|
|Scarlets 27 - 20 Zebre|
|Benetton Treviso 45 - 27 Newport Gwent D'gons|
|Friday 11th April|
|Edinburgh 22 - 29 Cardiff Blues|
|Ulster 58 - 12 Connacht|
|Ospreys 25 - 19 Leinster|
|Friday 4th April|
|Glasgow 29 - 10 Benetton Treviso|
|Thursday 3rd April|
|Newport Gwent D'gons 19 - 23 Edinburgh|
|Sunday 30th March|
|Scarlets 32 - 30 Connacht|
|Saturday 29th March|
|Leinster 22 - 18 Munster|
|Cardiff Blues 28 - 23 Ulster|
|Benetton Treviso 20 - 16 Edinburgh|
|Zebre 25 - 25 Newport Gwent D'gons|
|Friday 28th March|
|Glasgow 11 - 9 Ospreys|
|Sunday 23rd March|
|Newport Gwent D'gons 8 - 24 Connacht|
|Saturday 22nd March|
|Munster 14 - 3 Benetton Treviso|
|Glasgow 14 - 6 Scarlets|
|Friday 21st March|
|Edinburgh 3 - 9 Ulster|
|Leinster 27 - 0 Zebre|
Read the thoughts and opinions of Stuart Barnes with skysports.com