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Harlequins will have the services of ace fly-half Nick Evans available to them when they host Exeter in an Aviva Premiership clash on Saturday.
Evans has been sidelined by an ankle injury but returns to action at the expense of Ben Botica who drops to the bench.
Conor O'Shea has made two further changes to the team that beat Sale last weekend. Skipper Nick Easter moves from number eight into the second row in place of Charlie Matthews with Tom Guest taking over at the back of the scrum.
Exeter enter the encounter with the defending champions on a high after thrashing London Welsh 47-16 last time out.
The victory came at a price though, with prop Hoani Tui, lock Dean Mumm and centre Jason Shoemark all ruled out through injury.
The trio are replaced by Alex Brown, Damian Welch and Phil Dollman respectively.
Harlequins: 15 Ollie Lindsay-Hague, 14 Tom Williams, 13 Matt Hopper, 12 Jordan Turner-Hall, 11 Ugo Monye, 10 Nick Evans, 9 Karl Dickson, 8 Tom Guest, 7 Luke Wallace, 6 Maurie Fa'asavalu, 5 George Robson, 4 Nick Easter (C), 3 James Johnston, 2 Joe Gray, 1 Mark Lambert.
Replacements: 16 Rob Buchanan, 17 Darryl Marfo, 18 Will Collier, 19 Charlie Matthews, 20 Joe Trayfoot, 21 Jordan Burns, 22 Ben Botica, 23 George
Exeter Chiefs: 15 Luke Arscott, 14 Jack Nowell, 13 Sireli Naqelevuki, 12 Phil Dollman, 11 Matt Jess, 10 Gareth Steenson, 9 Haydn Thomas, 8 RichardBaxter, 7 James Scaysbrook, 6 Ben White, 5 Damian Welch, 4 Tom Hayes, 3 Alex Brown, 2 Jack Yeandle, 1 Carl Rimmer.
Replacements: 16 Neil Clark, 17 Ben Moon, 18 Craig Mitchell, 19 James Hanks, 20 Dave Ewers, 21 Will Chudley, 22 Ignacio Mieres, 23 Ian Whitten.
"Last week was a very good performance from us, but now we've got to make sure London Welsh was not a one-off performance and that we show the same enthusiasm and attacking intent for the rest of the season."
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|Saturday 25th May|
|15:00||Leicester vs Northampton|
|Sunday 12th May|
|Saracens 13 - 27 Northampton|
|Saturday 11th May|
|Leicester 33 - 16 Harlequins|
|Saturday 4th May|
|Leicester 32 - 20 London Irish|
|London Welsh 33 - 22 Worcester|
|Harlequins 22 - 19 Northampton|
|Sale 21 - 20 Wasps|
|Exeter 40 - 39 Gloucester|
|Saracens 23 - 14 Bath|
|Sunday 21st April|
|Wasps 24 - 37 Exeter|
|Saturday 20th April|
|Northampton 47 - 7 Sale|
|Gloucester 28 - 23 Saracens|
|London Irish 47 - 28 London Welsh|
|Worcester 26 - 42 Harlequins|
|Bath 27 - 26 Leicester|
|Sunday 14th April|
|Leicester 35 - 16 Wasps|
|Saracens 47 - 17 Worcester|
|London Welsh 14 - 31 Northampton|
|Saturday 13th April|
|Exeter 27 - 6 London Irish|
|Harlequins 23 - 9 Bath|
|Friday 12th April|
|Sale 32 - 9 Gloucester|
Read the thoughts and opinions of Stuart Barnes with skysports.com