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Gloucester have made five changes ahead of their Aviva Premiership clash against league leaders Saracens at Kingsholm on Saturday.
Director of Rugby Nigel Davies makes front and back line changes in an attempt to keep Gloucester's play-off ambitions alive.
Injuries sustained by Huia Edmonds and Dario Chistolini at Sale last week mean Koree Britton and Shaun Knight start in the front row.
The changes see Tom Savage move into the second row as well as assume the captaincy while Sione Kalamafoni starts in the flanks with Ben Morgan wearing the number eight jersey on his return after spending four months out.
In the backs Charlie Sharples returns to the right wing while Henry Trinder gets the nod ahead of Mike Tindall at centre where he will partner Billy Twelvetrees.
Meanwhile top-of-the-table Saracens travel to Gloucester with six changes in personnel with an international trio rested with the play-offs in sight.
Mark McCall has opted to start Owen Farrell at centre while Richard Wigglesworth returns to the side at scrum-half.
Captain Steve Borthwick, Alistair Hargreaves, Will Fraser and Ernst Joubert all return to the pack following absences.
England backs Chris Ashton and Brad Barritt both sit out of the visit to Gloucester as does Scotland forward Kelly Brown.
Gloucester enter the clash five points adrift of the play-off places while Saracens hold a comfortable four-point advantage at the head of the table.
Saracens: 15 Alex Goode, 14 Chris Wyles, 13 Joel Tomkins, 12 Owen Farrell, 11 David Strettle, 10 Charlie Hodgson, 9 Richard Wigglesworth, 8 Ernst Joubert, 7 Will Fraser, 6 Jackson Wray, 5 Alistair Hargreaves, 4 Steve Borthwick (capt), 3 Matt Stevens, 2 John Smit, 1 Rhys Gill.
Replacements:16 Jamie George, 17 Mako Vunipola, 18 Carlos Nieto, 19 George Kruis, 20 Jacques Burger, 21 Ben Spencer, 22 Duncan Taylor, 23 Joe Maddock.
Gloucester:15 Rob Cook, 14 Charlie Sharples, 13 Henry Trinder, 12 Billy Twelvetrees, 11 Jonny May, 10 Freddie Burns, 9 Dan Robson, 8 Nick Wood, 7 Koree Britton, 6 Shaun Knight, 5 Tom Savage (capt), 4 Lua Lokotui, 3 Sione Kalamafoni, 2 Akapusi Qera, 1 Ben Morgan.
Replacements:16 Tommaso d'Apice, 17 Dan Murphy, 18 Yann Thomas, 19 Peter Buxton, 20 Andy Hazell, 21 Dave Lewis, 22 Ryan Mills, 23 Martyn Thomas.
"You have to give Saracens credit, they're a very efficient side. They know what they do, and they do it very well.
"We have to be on our mettle on Saturday. We have to be clear about what our game plan is. The real battle will be about the gain line both with and without the ball, and both teams will be looking to win that battle. It's going to be a physical encounter."
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|Friday 20th December|
|20:00||Sale Sharks vs London Irish|
|Saturday 21st December|
|15:00||Exeter vs Newcastle|
|15:00||Bath vs Harlequins|
|15:00||Wasps vs Northampton|
|15:00||Saracens vs Leicester|
|Friday 27th December|
|TBC||Newcastle vs Wasps|
|Saturday 28th December|
|15:00||Northampton vs Bath|
|15:00||Worcester vs Saracens|
|15:00||Harlequins vs Exeter|
|15:00||Leicester vs Sale Sharks|
|Friday 3rd January|
|19:45||Newcastle vs Sale Sharks|
|Saturday 4th January|
|15:00||London Irish vs Worcester|
|15:00||Gloucester vs Saracens|
|15:00||Leicester vs Bath|
|Sunday 5th January|
|15:00||Wasps vs Exeter|
|Friday 7th February|
|19:45||Worcester vs Leicester|
|20:00||Sale Sharks vs Gloucester|
|Saturday 8th February|
|15:00||Harlequins vs Wasps|
|15:00||Bath vs Newcastle|
|15:00||Exeter vs Northampton|
|Sunday 9th February|
|15:00||Saracens vs London Irish|
|Friday 14th February|
|20:00||Sale Sharks vs Saracens|
|Saturday 15th February|
|15:00||Wasps vs London Irish|
|15:00||Northampton vs Worcester|
|15:00||Leicester vs Gloucester|
|Sunday 1st December|
|Newcastle 9 - 35 Harlequins|
|Saturday 30th November|
|Bath 21 - 16 Exeter|
|Worcester 10 - 33 Northampton|
|London Irish 12 - 19 Wasps|
|Saracens 24 - 19 Sale Sharks|
|Friday 29th November|
|Gloucester 17 - 22 Leicester|
|Sunday 24th November|
|Wasps 5 - 28 Bath|
|Saturday 23rd November|
|Northampton 18 - 0 Newcastle|
|Harlequins 27 - 19 Gloucester|
|Exeter 9 - 16 Saracens|
|Leicester 20 - 11 London Irish|
|Friday 22nd November|
|Sale Sharks 26 - 10 Worcester|
|Sunday 3rd November|
|Saracens 40 - 3 Newcastle|
|London Irish 14 - 19 Northampton|
|Saturday 2nd November|
|Leicester 16 - 23 Harlequins|
|Gloucester 30 - 32 Wasps|
|Friday 1st November|
|Sale Sharks 16 - 18 Exeter|
|Worcester 6 - 21 Bath|
|Sunday 27th October|
|Newcastle 13 - 11 London Irish|
|Wasps 22 - 12 Leicester|
|Saturday 26th October|
|Northampton 41 - 20 Saracens|
|Exeter 40 - 6 Worcester|
|Harlequins 24 - 3 Sale Sharks|
|Friday 25th October|
|Bath 15 - 13 Gloucester|
Read the thoughts and opinions of Stuart Barnes with skysports.com