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Harlequins will field the same side that won last year's Premiership final as they look to book their return to the play-offs with a win over Worcester at Sixways.
Quins boss Conor O'Shea names his title-winning XV for the first time this season, knowing that a win will book their play-off place after they ended a run of three successive defeats last week by beating Bath.
James Johnston will make his 100th appearance for the club and is named in the front-row with Joe Gray and Joe Marler, while George Robson has recovered from a knock he picked up last week and starts in the second-row, while Nick Easter, who starts at number eight, will make his 200th appearance for the club.
There are two changes in the backline from the side that defeated Bath last weekend as Jordan Turner-Hall is named at inside centre, while Ugo Monye starts on the left wing.
Matt Hopper had surgery on a finger injury on Monday and will be out for 14 weeks, while Tom Casson is still struggling with a knee injury sustained against Munster.
Worcester have lost eight out of their last nine games and have been beaten by Harlequins in each of their last 11 meetings, but will hope to end that streak in what will be Andy Goode's last appearance at Sixways before he joins Wasps.
Worcester wing Ben Howard will make his first Premiership start and Jon Clarke is named at inside centre in place of the suspended Josh Matavesi.
Matt Mullan and Matt Kvesic will also be making their final Sixways appearances for the Warriors before moving to Gloucester and London Wasps respectively.
Craig Gillies and Shaun Perry are recalled to the bench as Warriors search for their sixth Premiership win of the season.
Worcester: 15 Chris Pennell, 14 Josh Drauniniu, 13 Alex Grove, 12 Jon Clarke, 11 Ben Howard, 10 Andy Goode, 9 Jonny Arr, 8 Semisi Taulava, 7 Matt Kvesic, 6 Neil Best, 5 Chris Jones, 4 James Percival (c), 3 Euan Murray, 2 Ed Shervington, 1 Matt Mullan.
Replacements: 16 Aleki Lutui, 17 Rob O'Donnell, 18 John Andress, 19 Craig Gillies, 20 Jake Abbott, 21 Shaun Perry, 22 Danny Gray, 23 Joe Carlisle.
Harlequins: 15 Mike Brown, 14 Tom Williams, 13 George Lowe, 12 Jordan Turner-Hall, 11 Ugo Monye, 10 Nick Evans, 9 Danny Care, 8 Nick Easter, 7 Chris Robshaw, 6 Maurie Fa'asavalu, 5 George Robson, 4 Olly Kohn, 3 James Johnston, 2 Joe Gray, 1 Joe Marler.
Replacements: 16 Rob Buchanan, 17 Mark Lambert, 18 Will Collier, 19 Charlie Matthews, 20 Tom Guest,, 21 Karl Dickson, 22 Ben Botica, 23 Ross Chisholm.
Worcester coach Nigel Redman
"We have picked a team with a lot of Worcester influence and we want the players to give that extra bit. If they all do that, it will be enough.
"It's important for everyone concerned that we play with intent. Every game is a fresh occasion and a new opportunity and we will play with a positive mindset and aim to win the game.
"We have been competitive in most matches this season. Sometimes we have come up short and we are all responsible for that. When you look at our performances in some of our matches, we have looked like a very good team.
"We expect Harlequins to arrive at Sixways and play like champions. They won the Aviva Premiership title last season and will come here looking to secure a top four place."
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|Friday 2nd May|
|19:45||Bath vs Northampton|
|Saturday 3rd May|
|15:00||Saracens vs Worcester|
|15:00||Wasps vs Newcastle|
|15:00||Gloucester vs London Irish|
|15:15||Sale vs Leicester|
|Sunday 4th May|
|14:00||Exeter vs Harlequins|
|Saturday 10th May|
|15:15||Newcastle vs Exeter|
|15:15||Northampton vs Wasps|
|15:15||Worcester vs Gloucester|
|15:15||Leicester vs Saracens|
|15:15||Harlequins vs Bath|
|15:15||London Irish vs Sale|
|Sunday 20th April|
|Newcastle 18 - 23 Saracens|
|Northampton 36 - 21 London Irish|
|Saturday 19th April|
|Wasps 38 - 30 Gloucester|
|Bath 32 - 20 Worcester|
|Exeter 12 - 55 Sale|
|Friday 18th April|
|Harlequins 24 - 20 Leicester|
|Sunday 13th April|
|London Irish 40 - 12 Newcastle|
|Saracens 28 - 24 Northampton|
|Saturday 12th April|
|Gloucester 17 - 18 Bath|
|Worcester 33 - 38 Exeter|
|Leicester 27 - 15 Wasps|
|Friday 11th April|
|Sale Sharks 12 - 27 Harlequins|
|Sunday 30th March|
|Newcastle 12 - 17 Worcester|
|Saturday 29th March|
|Northampton 16 - 22 Leicester|
|Wasps 20 - 32 Saracens|
|Exeter 13 - 14 Gloucester|
|Harlequins 23 - 9 London Irish|
|Friday 28th March|
|Bath 11 - 12 Sale Sharks|
|Sunday 23rd March|
|Leicester 45 - 15 Exeter|
|Saturday 22nd March|
|London Irish 23 - 44 Bath|
|Saracens 39 - 17 Harlequins|
|Gloucester 40 - 33 Newcastle|
|Sale Sharks 19 - 6 Northampton|
|Friday 21st March|
|Worcester 11 - 13 Wasps|
Read the thoughts and opinions of Stuart Barnes with skysports.com