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Zebre will be without injured fly-half Luciano Orquera for Friday's PRO12 clash with reigning champions the Ospreys at Stadio XXV Aprile.
Orquera has a sprained ankle and is replaced by Alberto Chiesa in the number 10 jersey while Giovanbattista Venditti returns on the wing.
In the only other change to Christian Gajan's starting line-up, Emiliano Caffini is included ahead of Filippo Cristiano on the blindside.
There is a great deal of movement on the bench however as Carlo Festuccia, Salvatore Perugini, Flavio Tripodi, Filippo Ferrarini, Josh Sole, Alberto Benettin and Leonardo Sarto all make the squad.
Ospreys back rowers Justin Tipuric and Joe Bearman are injury concerns and will be monitored before the trip to Italy.
Prop Adam Jones is set to make his first start of the season after making his comeback from injury against Munster last weekend.
Zebre: 15 D Halangahu, 14 G Venditti, 13 M Pratichetti, 12 G Garcia (capt), 11 S Sinoti, 10 A Chiesa, 9 A Chillon, 8 Andries Van Schalkwyk, 7 M Bergamasco, 6 E Caffini, 5 M Van Vuren, 4 Q Geldenhuys, 3 L Redolfini, 2 Davide Giazzon, 1 Matias Aguero. Replacements: 16 C Festuccia, 17 S Perugini, 18 F Tripodi, 19 F Ferrarini, 20 J Sole, 21 L Martinelli, 22 A Benettin, 23 L Sarto.
Ospreys: 15 R Fussell, 14 H Dirksen, 13 A Beck, 12 A Bishop, 11 E Walker, 10 D Biggar, 9 K Fotuali'I, 1 R Bevington, 2 S Baldwin, 3 Adam Jones, 4 Alun Wyn Jones (Capt), 5 Ian Evans, 6 Ryan Jones, 7 Sam Lewis, 8 Jonathan Thomas, Replacements: 16 R Hibbard, 17 D Jones, 18 A Jarvis, 19 J Bearman, 20 G Stowers, 21 R Webb, 22 R Jones, 23 J Spratt
"I know they are bottom of the league but a couple of their games could have gone either way - the Glasgow game and certainly the defeat to Connacht," he said.
"We've gone out to Italy before and Italian sides have played particularly well against us. They are competitive, dangerous and I find them to be very inventive teams."
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|Saturday 25th May|
|16:45||Ulster vs Leinster|
|Saturday 11th May|
|Leinster 17 - 15 Glasgow|
|Friday 10th May|
|Ulster 28 - 17 Scarlets|
|Friday 3rd May|
|Edinburgh 31 - 24 Newport Gwent D'gons|
|Connacht 3 - 20 Glasgow|
|Zebre 25 - 27 Munster|
|Scarlets 17 - 41 Benetton Treviso|
|Leinster 37 - 19 Ospreys|
|Ulster 37 - 13 Cardiff Blues|
|Friday 26th April|
|Benetton Treviso 23 - 23 Connacht|
|Sunday 21st April|
|Zebre 22 - 41 Leinster|
|Saturday 20th April|
|Scarlets 24 - 6 Cardiff Blues|
|Friday 19th April|
|Connacht 18 - 34 Ulster|
|Glasgow 35 - 17 Ospreys|
|Benetton Treviso 30 - 10 Edinburgh|
|Newport Gwent D'gons 30 - 24 Munster|
|Saturday 13th April|
|Ospreys 28 - 3 Benetton Treviso|
|Munster 16 - 22 Leinster|
|Cardiff Blues 28 - 13 Zebre|
|Friday 12th April|
|Edinburgh 24 - 32 Connacht|
|Ulster 31 - 5 Newport Gwent D'gons|
|Scarlets 29 - 6 Glasgow|
Read the thoughts and opinions of Stuart Barnes with skysports.com