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Zebre will be without injured fly-half Luciano Orquera for Friday's PRO12 clash with reigning champions the Ospreys at Stadio XXV Aprile.
Orquera has a sprained ankle and is replaced by Alberto Chiesa in the number 10 jersey while Giovanbattista Venditti returns on the wing.
In the only other change to Christian Gajan's starting line-up, Emiliano Caffini is included ahead of Filippo Cristiano on the blindside.
There is a great deal of movement on the bench however as Carlo Festuccia, Salvatore Perugini, Flavio Tripodi, Filippo Ferrarini, Josh Sole, Alberto Benettin and Leonardo Sarto all make the squad.
Ospreys back rowers Justin Tipuric and Joe Bearman are injury concerns and will be monitored before the trip to Italy.
Prop Adam Jones is set to make his first start of the season after making his comeback from injury against Munster last weekend.
Zebre: 15 D Halangahu, 14 G Venditti, 13 M Pratichetti, 12 G Garcia (capt), 11 S Sinoti, 10 A Chiesa, 9 A Chillon, 8 Andries Van Schalkwyk, 7 M Bergamasco, 6 E Caffini, 5 M Van Vuren, 4 Q Geldenhuys, 3 L Redolfini, 2 Davide Giazzon, 1 Matias Aguero. Replacements: 16 C Festuccia, 17 S Perugini, 18 F Tripodi, 19 F Ferrarini, 20 J Sole, 21 L Martinelli, 22 A Benettin, 23 L Sarto.
Ospreys: 15 R Fussell, 14 H Dirksen, 13 A Beck, 12 A Bishop, 11 E Walker, 10 D Biggar, 9 K Fotuali'I, 1 R Bevington, 2 S Baldwin, 3 Adam Jones, 4 Alun Wyn Jones (Capt), 5 Ian Evans, 6 Ryan Jones, 7 Sam Lewis, 8 Jonathan Thomas, Replacements: 16 R Hibbard, 17 D Jones, 18 A Jarvis, 19 J Bearman, 20 G Stowers, 21 R Webb, 22 R Jones, 23 J Spratt
"I know they are bottom of the league but a couple of their games could have gone either way - the Glasgow game and certainly the defeat to Connacht," he said.
"We've gone out to Italy before and Italian sides have played particularly well against us. They are competitive, dangerous and I find them to be very inventive teams."
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|Friday 21st March|
|19:05||Ospreys vs Cardiff Blues|
|19:15||Leinster vs Zebre|
|19:45||Edinburgh vs Ulster|
|Saturday 22nd March|
|18:30||Glasgow vs Scarlets|
|19:15||Munster vs Benetton Treviso|
|Sunday 23rd March|
|15:05||Newport Gwent D'gons vs Connacht|
|Saturday 29th March|
|15:00||Zebre vs Newport Gwent D'gons|
|18:00||Benetton Treviso vs Edinburgh|
|18:30||Cardiff Blues vs Ulster|
|19:00||Leinster vs Munster|
|Sunday 30th March|
|14:05||Scarlets vs Connacht|
|Thursday 3rd April|
|18:30||Newport Gwent D'gons vs Edinburgh|
|Friday 11th April|
|19:05||Ulster vs Connacht|
|19:05||Ospreys vs Leinster|
|19:45||Edinburgh vs Cardiff Blues|
|Saturday 12th April|
|18:00||Benetton Treviso vs Newport Gwent D'gons|
|18:30||Munster vs Glasgow|
|18:30||Scarlets vs Zebre|
|Saturday 19th April|
|15:00||Zebre vs Edinburgh|
|15:00||Glasgow vs Ulster|
|15:00||Leinster vs Benetton Treviso|
|15:00||Connacht vs Munster|
|Sunday 20th April|
|14:00||Cardiff Blues vs Scarlets|
|16:45||Newport Gwent D'gons vs Ospreys|
|Saturday 3rd May|
|15:00||Zebre vs Ospreys|
|Friday 14th March|
|Ulster 26 - 13 Scarlets|
|Saturday 1st March|
|Leinster 28 - 25 Glasgow|
|Scarlets 18 - 13 Munster|
|Connacht 38 - 6 Benetton Treviso|
|Zebre 15 - 10 Cardiff Blues|
|Friday 28th February|
|Edinburgh 31 - 25 Ospreys|
|Ulster 38 - 8 Newport Gwent D'gons|
|Sunday 23rd February|
|Zebre 19 - 27 Connacht|
|Ospreys 11 - 25 Munster|
|Newport Gwent D'gons 24 - 23 Glasgow|
|Benetton Treviso 12 - 14 Ulster|
|Saturday 22nd February|
|Scarlets 25 - 21 Edinburgh|
|Thursday 20th February|
|Cardiff Blues 22 - 34 Leinster|
|Sunday 16th February|
|Ospreys 75 - 7 Benetton Treviso|
|Saturday 15th February|
|Munster 36 - 8 Zebre|
|Cardiff Blues 20 - 27 Glasgow|
|Connacht 11 - 7 Edinburgh|
|Friday 14th February|
|Leinster 31 - 19 Newport Gwent D'gons|
|Sunday 9th February|
|Zebre 8 - 31 Leinster|
|Glasgow 8 - 6 Connacht|
|Saturday 8th February|
|Munster 54 - 13 Cardiff Blues|
|Benetton Treviso 33 - 41 Scarlets|
|Friday 7th February|
|Ulster 10 - 7 Ospreys|
Read the thoughts and opinions of Stuart Barnes with skysports.com