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Worcester Warriors have made wholesale changes to their line-up for the visit of Sale to Sixways tonight.
Following a 90-3 thumping of Rovigo in the Amlin Challenge Cup, Chris Pennell, Alex Grove, Josh Matavesi, Andy Goode and Paul Hodgson come into the back division.
There is a further positional switch with Errie Claassens moving to the wing to accommodate the return of Pennell.
In the pack Matt Mullan, who will captain the side, Aleki Lutui, John Andress and James Percival are handed starts.
Sale Sharks made eight changes to their original line-up following their loss to Montpellier.
Five of the changes come in the pack - with the forwards having been criticised on the back of a disappointing start to the season.
Andy Powell, Richie Vernon, Richie Gray and Tommy Taylor all come into the side, with England Under-20s prop Ross Harrison handed his first start.
In the backs Johnny Leota and Sam Tuitupou tighten up the midfield, while Nick Macleod is handed the No 15 jersey.
They were also forced into a late change when lock Richie Gray suffered a reaction to his ankle injury in a fitness test at the team hotel.
His place will be taken by Kearnan Myall with Mark Easter coming in to take Myall's place on the bench
Worcester: 15 Chris Pennell, 14 Errie Claassens, 13 Alex Grove, 12 Josh Matavesi, 11 David Lemi, 10 Andy Goode, 9 Paul Hodgson, 8 Semisi Taulava, 7 Matt Kvesic, 6 Sam Betty, 5 Craig Gillies, 4 James Percival, 3 John Andress, 2 Aleki Lutui, 1 Matt Mullan (c).
Replacements: 16 Ed Shervington, 17 Ceri Jones, 18 James Currie, 19 Dean Schofield, 20 Chris Jones, 21 Jonny Arr, 22 Joe Carlisle, 23 Ravai Fatiaki.
Sale: 15 Nick Macleod, 14 Tom Brady, 13 Johnny Leota, 12 Sam Tuitupou, 11 Mark Cueto, 10 Danny Cipriani, 9 Cillian Willis, 8 Andy Powell, 7 David Seymour (capt), 6 Richie Vernon, 5 Fraser McKenzie, 4 Kearnan Myall, 3 Tony Buckley, 2 Tommy Taylor, 1 Ross Harrison.
Replacements: 16 Joe Ward, 17 Eifion Lewis-Roberts, 18 Vadim Cobilas, 19 Mark Easter, 20 James Gaskell, 21 Nathan Fowles, 22 Rob Miller, 23 Will Addison.
"We're looking forward to getting back into the Aviva Premiership after a spell in Europe. It has given other players the chance to stake their claim, but we are excited about the league and have some big games coming up.
"The games in Europe give you the chance to see which players will respond and put their hands up for selection.
"There are changes and it is only fair if players have worked hard that they are given a chance. We will have the most powerful squad out this season. The injury list has got gradually smaller and we only have a handful of players ruled out.
"That brings nice problems and I have real competition for places. It means one or two very good players will miss out, but I do expect them to come off the bench and make an impact."
"It's a massive match for us, and for Worcester as well. They'll be looking for a big performance after two high scoring wins in the Amlin Challenge Cup and we had a great result against Cardiff, followed by a tough match at Montpellier.
"We've got make sure that we're focused on the game, not on the table. Our emphasis is to be very disciplined and be clear about our game plan. Away matches like this are tough, and Friday evening will be a massive challenge for us."
|Click here for more betting|
|Friday 21st March|
|19:45||Worcester vs Wasps|
|Saturday 22nd March|
|14:00||Sale vs Northampton|
|15:00||Gloucester vs Newcastle|
|15:15||Saracens vs Harlequins|
|17:30||London Irish vs Bath|
|Sunday 23rd March|
|14:00||Leicester vs Exeter|
|Friday 28th March|
|19:45||Bath vs Sale|
|Saturday 29th March|
|15:00||Wasps vs Saracens|
|15:00||Harlequins vs London Irish|
|15:00||Exeter vs Gloucester|
|15:15||Northampton vs Leicester|
|Sunday 30th March|
|14:00||Newcastle vs Worcester|
|Friday 11th April|
|19:45||Sale vs Harlequins|
|Saturday 12th April|
|15:00||Worcester vs Exeter|
|15:00||Leicester vs Wasps|
|15:15||Gloucester vs Bath|
|Sunday 13th April|
|14:00||Saracens vs Northampton|
|15:00||London Irish vs Newcastle|
|Friday 18th April|
|19:45||Harlequins vs Leicester|
|Saturday 19th April|
|15:00||Bath vs Worcester|
|15:00||Exeter vs Sale Sharks|
|15:15||Wasps vs Gloucester|
|Sunday 20th April|
|14:00||Northampton vs London Irish|
|15:00||Newcastle vs Saracens|
|Saturday 3rd May|
|15:00||Bath vs Northampton|
|Sunday 2nd March|
|Newcastle 18 - 41 Leicester|
|Saturday 1st March|
|Northampton 39 - 13 Gloucester|
|Exeter 18 - 0 London Irish|
|Harlequins 21 - 20 Worcester|
|Wasps 17 - 21 Sale Sharks|
|Friday 28th February|
|Bath 10 - 23 Saracens|
|Sunday 23rd February|
|Saracens 23 - 10 Exeter|
|Newcastle 16 - 22 Northampton|
|London Irish 15 - 20 Leicester|
|Saturday 22nd February|
|Worcester 12 - 24 Sale Sharks|
|Bath 32 - 25 Wasps|
|Gloucester 25 - 20 Harlequins|
|Sunday 16th February|
|Leicester 11 - 8 Gloucester|
|Saturday 15th February|
|Exeter 23 - 27 Bath|
|Wasps 20 - 23 London Irish|
|Northampton 30 - 14 Worcester|
|Harlequins 18 - 14 Newcastle|
|Friday 14th February|
|Sale Sharks 10 - 15 Saracens|
|Sunday 9th February|
|Harlequins 11 - 10 Wasps|
|Saturday 8th February|
|Exeter 16 - 17 Northampton|
|Saracens 13 - 22 London Irish|
|Bath 24 - 6 Newcastle|
|Friday 7th February|
|Sale Sharks 24 - 19 Gloucester|
|Worcester 22 - 23 Leicester|
Read the thoughts and opinions of Stuart Barnes with skysports.com