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Leo Cullen leads a team which shows a blend of youth and experience for Leinster's trip to Cardiff Blues.
Ian Madigan partners Ireland international Isaac Boss at half-back with Andrew Goodman lining up at centre alongside Brendan Macken.
Out wide Andrew Conway is joined by Darren Hudson and, while Dave Kearney starts at full-back.
Dominic Ryan makes just his third appearance after an injury interrupted season thus far and he completes an exciting back-row alongside Shane Jennings and Jordi Murphy.
Leinster 'A' team skipper Jack McGrath is rewarded with a start in the front row after putting in strong performances in the British and Irish Cup
Meanwhile, Cardiff are also missing internationals and are being led by centre Gavin Evans.
The Blues face a Leinster side that has won four straight games in all competitions since losing 19-27 to table topping Ulster at Ravenhill in December.
Cardiff Blues: 15 Jason Tovey, 14 Owen Williams, 13 Gavin Evans (capt), 12 Dafydd Hewitt, 11 Harry Robinson, 10 Rhys Patchell, 9 Lewis Jones, 8 Robin Copeland, 7 Rory Watts-Jones, 6 Michael Paterson, 5 James Down, 4 Macauley Cook, 3 Taufa'ao Filise, 2 Rhys Williams, 1 Sam Hobbs.
Replacements: 16 Marc Breeze, 17 Nathan Trevett, 18 Scott Andrews, 19 Luke Hamilton, 20 Josh Navidi, 21 Alex Walker, 22 Ceri Sweeney, 23 Richard Smith.
Leinster: 15 Dave Kearney, 14 Andrew Conway, 13 Brendan Macken, 12 Andrew Goodman, 11 Darren Hudson, 10 Ian Madigan, 9 Isaac Boss, 8 Jordi Murphy, 7 Shane Jennings, 6 Dominic Ryan, 5 Tom Denton, 4 Leo Cullen, 3 Michael Bent, 2 Aaron Dundon, 1 Jack McGrath.
Replacements: 16 Thomas Sexton, 17 Heinke Van Der Merwe, 18 Jamie Hagan, 19 Ben Marshall, 20 Rhys Ruddock, 21 John Cooney, 22 Noel Reid, 23 Fionn Carr.
"I have no doubt that we will be stronger going into the end of this season than we were last year. Next season we will be stronger again. Leinster are ahead of us in this process but we are heading in the right direction.
"For me, tomorrow's game has a bit of pride attached to what we have to deliver. Over in Dublin it was not a good performance.
"The second half was creditable but the first half we got hammered. I didn't enjoy that. I didn't enjoy the game or what happened afterwards. We have to lay a strong marker down on Friday. We have to put in a massive performance against one of the top squads in Europe.
"It is a great challenge for the team. We want to try and win the game and the next few games so we can keep pushing towards the top four."
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|Friday 18th April|
|17:00||Leinster vs Benetton Treviso|
|19:35||Glasgow vs Ulster|
|Saturday 19th April|
|14:30||Zebre vs Edinburgh|
|18:15||Connacht vs Munster|
|Sunday 20th April|
|14:00||Cardiff Blues vs Scarlets|
|16:45||Newport Gwent D'gons vs Ospreys|
|Saturday 26th April|
|19:05||Glasgow vs Edinburgh|
|Thursday 1st May|
|17:00||Zebre vs Ospreys|
|Friday 2nd May|
|19:00||Benetton Treviso vs Glasgow|
|19:05||Scarlets vs Newport Gwent D'gons|
|19:30||Ulster vs Leinster|
|Saturday 3rd May|
|17:00||Edinburgh vs Munster|
|17:00||Connacht vs Cardiff Blues|
|Saturday 10th May|
|18:30||Leinster vs Edinburgh|
|18:30||Ospreys vs Connacht|
|18:30||Newport Gwent D'gons vs Benetton Treviso|
|18:30||Munster vs Ulster|
|18:30||Scarlets vs Cardiff Blues|
|18:30||Glasgow vs Zebre|
|Saturday 12th April|
|Munster 5 - 22 Glasgow|
|Scarlets 27 - 20 Zebre|
|Benetton Treviso 45 - 27 Newport Gwent D'gons|
|Friday 11th April|
|Edinburgh 22 - 29 Cardiff Blues|
|Ulster 58 - 12 Connacht|
|Ospreys 25 - 19 Leinster|
|Friday 4th April|
|Glasgow 29 - 10 Benetton Treviso|
|Thursday 3rd April|
|Newport Gwent D'gons 19 - 23 Edinburgh|
|Sunday 30th March|
|Scarlets 32 - 30 Connacht|
|Saturday 29th March|
|Leinster 22 - 18 Munster|
|Cardiff Blues 28 - 23 Ulster|
|Benetton Treviso 20 - 16 Edinburgh|
|Zebre 25 - 25 Newport Gwent D'gons|
|Friday 28th March|
|Glasgow 11 - 9 Ospreys|
|Sunday 23rd March|
|Newport Gwent D'gons 8 - 24 Connacht|
|Saturday 22nd March|
|Munster 14 - 3 Benetton Treviso|
|Glasgow 14 - 6 Scarlets|
|Friday 21st March|
|Edinburgh 3 - 9 Ulster|
|Leinster 27 - 0 Zebre|
|Ospreys 34 - 9 Cardiff Blues|
|Friday 14th March|
|Ulster 26 - 13 Scarlets|
|Saturday 1st March|
|Leinster 28 - 25 Glasgow|
|Scarlets 18 - 13 Munster|
|Connacht 38 - 6 Benetton Treviso|
|Zebre 15 - 10 Cardiff Blues|
Read the thoughts and opinions of Stuart Barnes with skysports.com