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Exiles v Newcastle: Teams
Player to watch: Steve Jones - The former Border Reivers player only arrived at Kingston Park in the summer but has found himself handed the job of filling in at No 10 in the absence of Jonny Wilkinson and Toby Flood. After only 32 points in 21 appearances for the Scottish side, the pressure will be on Jones to deliver.
Match fact: The Exiles have won six out of their past seven games at the Madjeski Stadium, while the Falcons have not tasted victory on the road since beating Sale on November 17, 2006.
Betting: For the latest Guinness Premiership odds, click here.
At the Madejski Stadium, Sunday September 23, KO 3pm
London Irish are boosted by the return to fitness of captain Bob Casey and fly-half Shane Geraghty for the visit of Newcastle Falcons to the Madejski Stadium.
Casey missed the season-opening defeat at Harlequins due to a leg injury, but is fit to take his place in the second-row against Newcastle.
Geraghty - who has been rehabilitating a leg injury suffered while training with England back in June - is ready to feature in the starting line-up after being an unused replacement last week.
Casey, Geraghty and Dan Murphy are the three changes to the XV that lost at Twickenham, while Jeremy Staunton switches to inside centre to accommodate Geraghty.
Kieran Roche, Tonga Lea'aetoa and Nils Mordt all drop down to the replacements bench.
Falcons flying high
Newcastle director of rugby John Fletcher is refusing to get carried away after his side opened up their campaign with victory over Sale.
The Falcons overcame the 2006 champions 33-12 at Kingston Park, but Fletcher insists there are still areas for his side to work on.
He told the club's official website: "I expected a win, I thought we would win and we did win, but that's what the players are paid to do so you won't see us singing and dancing about it.
"Naturally a victory brings confidence, and winning is a habit so it's good to get off to a start like that so early in the season.
"It was a good start, not a perfect one, but to get five points from the game puts us in reasonable spirits going in to this weekend.
"Tactically we played much better, but there are still a lot of areas where we can improve so we're not patting ourselves on the back after one win."
Fletcher has been forced to make three changes - with Toby Flood teaming up with the England squad in France, while Mark Mayerhofler and Andy Buist have been ruled out through injury.
Steve Jones has been handed the task of filling Flood's boots, with Tom Dillon and Andy Perry replacing Mayerhofler and Buist respectively.
Newcastle do welcome John Rudd back on to the wing after he was forced to miss the win over Sale with an ankle injury, while South African No 8 Russell Winter is named on the bench.
London Irish: 15 Delon Armitage, 14 Topsy Ojo, 13 Mark Ireland, 12 Jeremy Staunton, 11 Tomas De Vedia, 10 Shane Geraghty, 9. Paul Hodgson; 1 Dan Murphy, 2 David Paice, 3 Faan Rautenbach, 4 Nick Kennedy, 5 Bob Casey (capt), 6 Declan Danaher, 7 Richard Thorpe, 8 Phil Murphy
Replacements: 16 Casey Dunning, 17 Stuart Mackie, 18 Tonga Lea'aetoa, 19 Kieran Roche, 20 Steffon Armitage, 21 Warren Fury, 22 Nils Mordt
Newcastle: 15 Matthew Burke, 14 Tom May, 13 Tom Dillon, 12 Joe Shaw, 11 John Rudd, 10 Steve Jones, 9 James Grindal, 1 Joe McDonnell, 2 Matt Thompson, 3 Micky Ward, 4 Andy Perry, 5 Mark Sorenson, 6 Geoff Parling, 7 Ben Woods, 8 Phil Dowson (capt)
Replacements: 16 Andy Long, 17 David Wilson, 18 Russell Winter, 19 Brent Wilson, 20 Lee Dickson, 21 Adam Dehaty, 22 Ollie Phillips
|Click here for more betting|
|Friday 13th February|
|19:45||Leicester vs Gloucester|
|19:45||Northampton vs London Irish|
|Saturday 14th February|
|16:30||Exeter vs Newcastle|
|Sunday 15th February|
|13:00||Saracens vs Bath|
|14:00||Wasps vs Harlequins|
|14:30||London Welsh vs Sale|
|Friday 20th February|
|19:45||Newcastle vs Wasps|
|Saturday 21st February|
|14:00||Sale vs Saracens|
|15:00||Harlequins vs Exeter|
|15:00||Gloucester vs London Welsh|
|15:15||Bath vs Northampton|
|Sunday 22nd February|
|14:00||London Irish vs Leicester|
|Friday 27th February|
|19:45||Leicester vs Sale|
|19:45||Northampton vs Harlequins|
|Saturday 28th February|
|14:30||London Welsh vs London Irish|
|15:00||Saracens vs Newcastle|
|15:15||Exeter vs Bath|
|Sunday 1st March|
|14:00||Wasps vs Gloucester|
|Friday 6th March|
|19:45||Bath vs Sale|
|Saturday 7th March|
|15:00||Exeter vs London Welsh|
|15:00||Harlequins vs London Irish|
|15:15||Gloucester vs Northampton|
|Sunday 8th March|
|14:00||Wasps vs Saracens|
|15:00||Newcastle vs Leicester|
|Friday 27th March|
|19:45||Northampton vs Wasps|
|Sunday 11th January|
|London Irish 28 - 26 Exeter|
|Newcastle 38 - 7 London Welsh|
|Saturday 10th January|
|Harlequins 32 - 12 Leicester|
|Bath 39 - 26 Wasps|
|Sale Sharks 20 - 7 Northampton|
|Friday 9th January|
|Gloucester 24 - 23 Saracens|
|Sunday 4th January|
|London Welsh 13 - 24 Harlequins|
|Wasps 41 - 16 Sale Sharks|
|Leicester 17 - 8 Bath|
|Saturday 3rd January|
|Exeter 25 - 26 Gloucester|
|Saracens 22 - 6 London Irish|
|Friday 2nd January|
|Northampton 39 - 31 Newcastle|
|Sunday 28th December|
|Gloucester 23 - 30 Wasps|
|Saturday 27th December|
|Harlequins 25 - 30 Northampton|
|Newcastle 23 - 25 Saracens|
|Bath 31 - 14 Exeter|
|Sale Sharks 30 - 32 Leicester|
|Friday 26th December|
|London Irish 24 - 9 London Welsh|
|Sunday 21st December|
|Wasps 48 - 16 London Irish|
|Saturday 20th December|
|Gloucester 16 - 39 Bath|
|Northampton 23 - 19 Leicester|
|Saracens 78 - 7 London Welsh|
|Harlequins 15 - 7 Newcastle|
|Friday 19th December|
|Sale 18 - 11 Exeter|
Read the thoughts and opinions of Phil Edwards with skysports.com