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It's at Kingsholm and it's against a side who we know can challenge us and can beat us. They've some dangerous players and we have to be ready for that.
Quotes of the week
Gloucester head coach Bryan Redpath is without 10 squad members for the visit of Harlequins in their Guinness Premiership clash this Saturday.
Several players are away on international duty for their respective countries limiting the selection choice for the seventh-placed outfit.
However there is some good news for Redpath as their England Saxons quartet returns with David Attwood, Nick Wood, Olly Morgan and Paul Doran Jones all coming into the squad.
Gloucester clinched a valuable victory against Harlequins last weekend in a 31-29 win, but head coach Redpath insists this doesn't give them a mental edge.
He said: "We've an opportunity to move up the table but it will only happen if we work hard and not because of what happened last weekend. It's a different game and back to the Premiership.
"Quins are not a bad side either. We have to get our heads around that. I'm not bothered about last weekend; it's about the next game.
"It's at Kingsholm and it's against a side who we know can challenge us and can beat us. They've some dangerous players and we have to be ready for that."
The home side are without Danny Wright, Freddie Burns, Jonny May, Jordi Pasqualin and Shaun Knight, who are still with the England U20s, while Rory Lawson, Alastair Dickinson, Scott Lawson and Ali Strokosch are with the Scotland squad ahead of their RBS Six Nations match against Wales.
Eliota Fuimaono-Sapolu, though, makes a return to the Gloucester side at inside centre along with Nicky Robinson playing at full-back.
Harlequins are determined to avenge the narrow defeat against Gloucester last weekend and they have been boosted by the return of three key players.
David Strettle returns from Saxons duty while Rory Clegg and Sam Smith are back from the England U20s.
Gonzalo Tiesi who was unable to compete in the last match due to fitness has been cleared to play and comes in at centre.
Gloucester: 15 Olly Morgan, 14 James Simpson-Daniel, 13 Tim Molenaar, 12 Eliota Fuimaono-Sapolu, 11 Lesley Vainikolo, 10 Nicky Robinson, 9 Dave Lewis, 8 Gareth Delve (capt), 7 Akapusi Qera, 6 Luke Narraway, 5 Alex Brown, 4 Dave Attwood, 3 Greg Somerville, 2 Olivier Azam, 1 Nick Wood.
Replacements: 16 Darren Dawidiuk, 17 Paul Doran-Jones, 18 Pierre Capdevielle, 19 Adam Eustace, 20 Andrew Hazell, 21 Rory Lawson, 22 Tim Taylor, 23 Tom Voyce.
Harlequins: 15 Mike Brown (capt), 14 David Strettle, 13 Gonzalo Tiesi, 12 Jordan Turner-Hall, 11 George Lowe, 10 Nick Evans, 9 Karl Dickson, 8 Tom Guest, 7 Neil McMillan, 6 Chris York, 5 Lewis Stevenson, 4 James Percival, 3 James Johnston, 2 Chris Brooker, 1 Ceri Jones.
Replacements: 16 Aston Croall, 17 Matt Cairns, 18 John Andress, 19 Tomas Vallejos, 20 Luke Wallace, 21 Steve So'oialo, 22 Rory Clegg, 23 Sam Smith.
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|Friday 20th December|
|20:00||Sale Sharks vs London Irish|
|Saturday 21st December|
|15:00||Exeter vs Newcastle|
|15:00||Bath vs Harlequins|
|15:00||Wasps vs Northampton|
|15:00||Saracens vs Leicester|
|Friday 27th December|
|TBC||Newcastle vs Wasps|
|Saturday 28th December|
|15:00||Northampton vs Bath|
|15:00||Worcester vs Saracens|
|15:00||Harlequins vs Exeter|
|15:00||Leicester vs Sale Sharks|
|Friday 3rd January|
|19:45||Newcastle vs Sale Sharks|
|Saturday 4th January|
|15:00||London Irish vs Worcester|
|15:00||Gloucester vs Saracens|
|15:00||Leicester vs Bath|
|Sunday 5th January|
|15:00||Wasps vs Exeter|
|Friday 7th February|
|19:45||Worcester vs Leicester|
|20:00||Sale Sharks vs Gloucester|
|Saturday 8th February|
|15:00||Harlequins vs Wasps|
|15:00||Bath vs Newcastle|
|15:00||Exeter vs Northampton|
|Sunday 9th February|
|15:00||Saracens vs London Irish|
|Friday 14th February|
|20:00||Sale Sharks vs Saracens|
|Saturday 15th February|
|15:00||Wasps vs London Irish|
|15:00||Northampton vs Worcester|
|15:00||Leicester vs Gloucester|
|Sunday 1st December|
|Newcastle 9 - 35 Harlequins|
|Saturday 30th November|
|Bath 21 - 16 Exeter|
|Worcester 10 - 33 Northampton|
|London Irish 12 - 19 Wasps|
|Saracens 24 - 19 Sale Sharks|
|Friday 29th November|
|Gloucester 17 - 22 Leicester|
|Sunday 24th November|
|Wasps 5 - 28 Bath|
|Saturday 23rd November|
|Northampton 18 - 0 Newcastle|
|Harlequins 27 - 19 Gloucester|
|Exeter 9 - 16 Saracens|
|Leicester 20 - 11 London Irish|
|Friday 22nd November|
|Sale Sharks 26 - 10 Worcester|
|Sunday 3rd November|
|Saracens 40 - 3 Newcastle|
|London Irish 14 - 19 Northampton|
|Saturday 2nd November|
|Leicester 16 - 23 Harlequins|
|Gloucester 30 - 32 Wasps|
|Friday 1st November|
|Sale Sharks 16 - 18 Exeter|
|Worcester 6 - 21 Bath|
|Sunday 27th October|
|Newcastle 13 - 11 London Irish|
|Wasps 22 - 12 Leicester|
|Saturday 26th October|
|Northampton 41 - 20 Saracens|
|Exeter 40 - 6 Worcester|
|Harlequins 24 - 3 Sale Sharks|
|Friday 25th October|
|Bath 15 - 13 Gloucester|
Read the thoughts and opinions of Stuart Barnes with skysports.com