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|Home team||Away Team|
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Northampton know a bonus-point victory over the Leicester in the East Midlands derby could see them leapfrog their rivals in the table.
Saints have beaten Wasps and Bath in recent league outings while the Tigers won all five of their games in March in all competitions, including a 26-14 LV= Cup win over Northampton.
With just three rounds of the Aviva Premiership remaining the closing stages of the campaign with not only dictate who clinches a play-off spot, but who wins a home semi-final as well.
Saints boss Jim Mallinder has made only one change to the team that started in last week's 26-6 victory at Bath.
Samu Manoa comes into the second row to partner Christian Day with Mark Sorenson dropping to the bench.
"It's a big game," Saints' director of rugby Jim Mallinder said this week. "Obviously Leicester are our local rivals, but we know that we've got three games to go in the regular season and we want to win all three to give us a chance of a home semi-final.
"That's what we're aiming for and I'm sure that everyone's going to be up for Saturday's game. We've trained hard and have prepared for what's going to come at us on Saturday. Leicester are physical up front and love the set piece, but they like to play a bit too and get on the front foot. So we'll have to be at the top of our game."
England international scrum-half Ben Youngs returns to the Tigers line-up after missing their bonus-point win over Worcester Warriors due to suspension.
He is re-united with international colleague Toby Flood at half-back while Horacio Agulla, George Skivington and Geoff Parling are included in the team after missing the Worcester fixture.
Tigers director of rugby Richard Cockerill said: "Tigers versus Saints is always a big match, no matter what is at stake. Both teams are chasing a place in the semi-finals and this promises to be another big occasion.
"These are two good set-piece teams, with two good sets of backs, and these games have been great contests."
Northampton:15 Ben Foden, 14 Chris Ashton, 13 George Pisi, 12 James Downey, 11 Paul Diggin, 10 Ryan Lamb, 9 Lee Dickson (capt), 8 Roger Wilson, 7 Phil Dowson, 6 James Craig, 5 Christian Day, 4 Samu Manoa, 3 Brian Mujati, 2 Andy Long, 1 Soane Tonga'uiha.
Replacements: 16 Ross McMillan, 17 Alex Waller, 18 Paul Doran-Jones, 19 Mark Sorenson,20 Ben Nutley, 21 Martin Roberts, 22 Stephen Myler, 23 Tom May.
Leicester Tigers: 15 Geordan Murphy (c), 14 Horacio Agulla, 13 Manusamoa Tuilagi, 12 Anthony Allen, 11 Alesana Tuilagi, 10 Toby Flood, 9 Ben Youngs, 8 Thomas Waldrom, 7 Julian Salvi, 6 Tom Croft, 5 Geoff Parling, 4 George Skivington, 3 Dan Cole, 2 George Chuter, 1 Marcos Ayerza.
Replacements: 16 Tom Youngs, 17 Martin Castrogiovanni, 18 Logovi'i Mulipola, 19 Steve Mafi, 20 Craig Newby, 21 Sam Harrison, 22 Billy Twelvetrees, 23 Scott Hamilton.
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|Friday 21st March|
|19:45||Worcester vs Wasps|
|Saturday 22nd March|
|14:00||Sale vs Northampton|
|15:00||Gloucester vs Newcastle|
|15:15||Saracens vs Harlequins|
|17:30||London Irish vs Bath|
|Sunday 23rd March|
|14:00||Leicester vs Exeter|
|Friday 28th March|
|19:45||Bath vs Sale|
|Saturday 29th March|
|15:00||Wasps vs Saracens|
|15:00||Harlequins vs London Irish|
|15:00||Exeter vs Gloucester|
|15:15||Northampton vs Leicester|
|Sunday 30th March|
|14:00||Newcastle vs Worcester|
|Friday 11th April|
|19:45||Sale vs Harlequins|
|Saturday 12th April|
|15:00||Worcester vs Exeter|
|15:00||Leicester vs Wasps|
|15:15||Gloucester vs Bath|
|Sunday 13th April|
|14:00||Saracens vs Northampton|
|15:00||London Irish vs Newcastle|
|Friday 18th April|
|19:45||Harlequins vs Leicester|
|Saturday 19th April|
|15:00||Bath vs Worcester|
|15:00||Exeter vs Sale Sharks|
|15:15||Wasps vs Gloucester|
|Sunday 20th April|
|14:00||Northampton vs London Irish|
|15:00||Newcastle vs Saracens|
|Saturday 3rd May|
|15:00||Bath vs Northampton|
|Sunday 2nd March|
|Newcastle 18 - 41 Leicester|
|Saturday 1st March|
|Northampton 39 - 13 Gloucester|
|Exeter 18 - 0 London Irish|
|Harlequins 21 - 20 Worcester|
|Wasps 17 - 21 Sale Sharks|
|Friday 28th February|
|Bath 10 - 23 Saracens|
|Sunday 23rd February|
|Saracens 23 - 10 Exeter|
|Newcastle 16 - 22 Northampton|
|London Irish 15 - 20 Leicester|
|Saturday 22nd February|
|Worcester 12 - 24 Sale Sharks|
|Bath 32 - 25 Wasps|
|Gloucester 25 - 20 Harlequins|
|Sunday 16th February|
|Leicester 11 - 8 Gloucester|
|Saturday 15th February|
|Exeter 23 - 27 Bath|
|Wasps 20 - 23 London Irish|
|Northampton 30 - 14 Worcester|
|Harlequins 18 - 14 Newcastle|
|Friday 14th February|
|Sale Sharks 10 - 15 Saracens|
|Sunday 9th February|
|Harlequins 11 - 10 Wasps|
|Saturday 8th February|
|Exeter 16 - 17 Northampton|
|Saracens 13 - 22 London Irish|
|Bath 24 - 6 Newcastle|
|Friday 7th February|
|Sale Sharks 24 - 19 Gloucester|
|Worcester 22 - 23 Leicester|
Read the thoughts and opinions of Stuart Barnes with skysports.com