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The Sharks will welcome dynamic prop Tendai 'Beast' Mtawarira to the fray for the first time this season when they face the Highlanders in Durban on Saturday.
Mtawarira injured his ankle during the Sharks' pre-season preparations and has not yet featured this season.
The Springbok star's return is one of three changes to the Sharks team that narrowly missed out against the Chiefs two weeks ago.
Elsewhere in the pack, impressive young flanker Marcell Coetzee takes over the number seven jersey from Willem Alberts.
There is a first start for another young gun as Paul Jordaan comes in at outside centre. Jordaan's arrival sees JP Pietersen switch to wing and Louis Ludik shift over to full-back. Riaan Viljoen drops out of the matchday 22.
Jannie du Plessis and Wiehahn Herbst are bracketed together at tighthead prop, with the former struggling to shake off a knock sustained against the Chiefs. Du Plessis will take some part in the encounter with the only question being whether it will be from the start or off the bench.
Coach John Plumtree has named a five-two forward split amongst his replacements, with number eight Ryan Kankowski featuring for the first time since injuring his finger in the opening round of the competition.
Highlanders team news to follow....
Sharks: 15 Louis Ludik, 14 JP Pietersen, 13 Paul Jordaan, 12 Tim Whitehead, 11 Lwazi Mvovo, 10 Patrick Lambie, 9 Charl McLeod, 8 Keegan Daniel (c), 7 Marcell Coetzee, 6 Jacques Botes, 5 Anton Bresler, 4 Steven Sykes, 3 Jannie du Plessis/Wiehahn Herbst, 2 Bismarck du Plessis, 1 Dale Chadwick.
Replacements: 16 Craig Burden, 17 Jannie du Plessis/Wiehahn Herbst, 18 Pieter-Steph du Toit, 19 Jean Deysel, 20 Ryan Kankowski, 21 Frederic Michalak, 22 Meyer Bosman.
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|Friday 24th May|
|08:35||Chiefs vs Crusaders|
|10:40||Melbourne Rebels vs Waratahs|
|Saturday 25th May|
|08:35||Blues vs Brumbies|
|10:40||Western Force vs Highlanders|
|16:00||Southern Kings vs Cheetahs|
|16:05||Stormers vs Reds|
|18:10||Sharks vs Bulls|
|Friday 31st May|
|08:35||Crusaders vs Waratahs|
|10:40||Brumbies vs Hurricanes|
|Saturday 1st June|
|08:35||Highlanders vs Blues|
|10:40||Reds vs Melbourne Rebels|
|16:05||Stormers vs Southern Kings|
|18:10||Cheetahs vs Bulls|
|Friday 7th June|
|10:40||Brumbies vs Melbourne Rebels|
|Sunday 9th June|
|07:05||Western Force vs Waratahs|
|Friday 28th June|
|08:35||Chiefs vs Hurricanes|
|Saturday 29th June|
|08:35||Highlanders vs Crusaders|
|14:00||Sharks vs Blues|
|16:05||Bulls vs Southern Kings|
|18:10||Stormers vs Cheetahs|
|Friday 5th July|
|08:35||Crusaders vs Chiefs|
|Saturday 6th July|
|08:35||Hurricanes vs Highlanders|
|14:00||Cheetahs vs Blues|
|16:05||Southern Kings vs Stormers|
|18:10||Bulls vs Sharks|
|Saturday 18th May|
|Cheetahs 27 - 13 Reds|
|Bulls 35 - 18 Highlanders|
|Waratahs 28 - 22 Brumbies|
|Crusaders 23 - 3 Blues|
|Friday 17th May|
|Western Force 13 - 23 Sharks|
|Melbourne Rebels 30 - 21 Stormers|
|Hurricanes 12 - 17 Chiefs|
|Saturday 11th May|
|Southern Kings 34 - 27 Highlanders|
|Waratahs 21 - 15 Stormers|
|Blues 36 - 32 Melbourne Rebels|
|Friday 10th May|
|Cheetahs 34 - 39 Hurricanes|
|Reds 32 - 17 Sharks|
|Chiefs 22 - 21 Western Force|
|Sunday 5th May|
|Brumbies 23 - 30 Crusaders|
|Saturday 4th May|
|Bulls 48 - 14 Hurricanes|
|Southern Kings 10 - 72 Waratahs|
|Western Force 11 - 11 Reds|
|Highlanders 25 - 22 Sharks|
|Friday 3rd May|
|Melbourne Rebels 33 - 39 Chiefs|
|Blues 18 - 17 Stormers|
|Sunday 28th April|
|Crusaders 30 - 26 Melbourne Rebels|
|Saturday 27th April|
|Cheetahs 26 - 12 Southern Kings|
|Bulls 30 - 19 Waratahs|
|Brumbies 41 - 7 Western Force|
|Chiefs 37 - 29 Sharks|
Read the thoughts and opinions of Stuart Barnes with skysports.com